Immunogenicity and protective efficacy of a novel bacterium-like particle-based vaccine displaying canine distemper virus antigens in mice and dogs

Immunogenicity and protective efficacy of a novel bacterium-like particle-based vaccine displaying canine distemper virus antigens in mice and dogs

ABSTRACTCanine distemper virus (CDV) poses a severe threat to both domesticated and wild animals, including multiple carnivores. With the continued expansion of its host range, there is an urgent need for the development of a safer and more effective vaccine. In this study, we developed subunit vacc...

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Bibliographic Details
Main Authors: Jianzhong Wang, Lina Liu, Xianchun Zong, Chunliu Wang, Guangmei Zhu, Guilian Yang, Yanlong Jiang, Wentao Yang, Haibin Huang, Chunwei Shi, Yan Zeng, Nan Wang, Xin Cao, Chunfeng Wang, Na Feng
Format: Article
Language:English
Published: American Society for Microbiology 2024-04-01
Series:Microbiology Spectrum
Subjects:
bacterium-like particles
canine distemper virus
subunit vaccine
surface display technology
immune response
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03477-23

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