Sur-X, a novel peptide, kills colorectal cancer cells by targeting survivin-XIAP complex

Sur-X, a novel peptide, kills colorectal cancer cells by targeting survivin-XIAP complex

Abstract Background Survivin and XIAP are two important members of the inhibitor of apoptosis protein family and have been considered as potential targets for cancer treatment due to their overexpression in large variety of cancers including colorectal cancer. It has been reported that survivin and...

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Bibliographic Details
Main Authors: Wanxia Fang, Xiaofang Che, Guohui Li, Anhui Wang, Yizhe Wang, Xiaonan Shi, Kezuo Hou, Xiaojie Zhang, Xiujuan Qu, Yunpeng Liu
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Colorectal cancer
Survivin-XIAP complex
Anticancer peptide
Apoptosis
Necroptosis
Online Access:http://link.springer.com/article/10.1186/s13046-020-01581-3

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