Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination?
Abstract Background The groundwork for malaria elimination does not currently consider the potential of Plasmodium zoonotic cycles that involve non-human primates (NHPs) in sylvatic environments. Since vivax malaria is less responsive to control measures, finding Plasmodium vivax infected NHPs adds...
| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-11-01
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| Series: | Malaria Journal |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12936-022-04349-6 |
| _version_ | 1797984008636727296 |
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| author | Bárbara Aparecida Chaves Denise Anete Madureira de Alvarenga Matheus de Oliveira Costa Pereira Marcelo Gordo Emanuelle L. Da Silva Edson Rodrigues Costa Aline Souza de Menezes Medeiros Igor José Martins Pedrosa Daniela Brito Maurício Teixeira Lima Maria Paula Mourão Wuelton M. Monteiro Nikos Vasilakis Cristiana Ferreira Alves de Brito Gisely C. Melo Marcus V. G. Lacerda |
| author_facet | Bárbara Aparecida Chaves Denise Anete Madureira de Alvarenga Matheus de Oliveira Costa Pereira Marcelo Gordo Emanuelle L. Da Silva Edson Rodrigues Costa Aline Souza de Menezes Medeiros Igor José Martins Pedrosa Daniela Brito Maurício Teixeira Lima Maria Paula Mourão Wuelton M. Monteiro Nikos Vasilakis Cristiana Ferreira Alves de Brito Gisely C. Melo Marcus V. G. Lacerda |
| author_sort | Bárbara Aparecida Chaves |
| collection | DOAJ |
| description | Abstract Background The groundwork for malaria elimination does not currently consider the potential of Plasmodium zoonotic cycles that involve non-human primates (NHPs) in sylvatic environments. Since vivax malaria is less responsive to control measures, finding Plasmodium vivax infected NHPs adds even more concern. Methods Both Free-living monkeys in forest fragments inside the urban area and captive monkeys from a local zoo had blood samples tested for Plasmodium species. Results In this study, among the Neotropical monkeys tested, three (4.4%), one captive and two free-living, were found to be naturally infected by P. vivax. Conclusion This important finding indicates that it is necessary to estimate the extent to which P. vivax NHP infection contributes to the maintenance of malaria transmission to humans. Therefore, the discussion on wildlife conservation and management must be incorporated into the malaria elimination agenda. |
| first_indexed | 2024-04-11T06:55:01Z |
| format | Article |
| id | doaj.art-d742a9d1db5b40d7ae6bb8893f92ede1 |
| institution | Directory Open Access Journal |
| issn | 1475-2875 |
| language | English |
| last_indexed | 2024-04-11T06:55:01Z |
| publishDate | 2022-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Malaria Journal |
| spelling | doaj.art-d742a9d1db5b40d7ae6bb8893f92ede12022-12-22T04:39:03ZengBMCMalaria Journal1475-28752022-11-012111710.1186/s12936-022-04349-6Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination?Bárbara Aparecida Chaves0Denise Anete Madureira de Alvarenga1Matheus de Oliveira Costa Pereira2Marcelo Gordo3Emanuelle L. Da Silva4Edson Rodrigues Costa5Aline Souza de Menezes Medeiros6Igor José Martins Pedrosa7Daniela Brito8Maurício Teixeira Lima9Maria Paula Mourão10Wuelton M. Monteiro11Nikos Vasilakis12Cristiana Ferreira Alves de Brito13Gisely C. Melo14Marcus V. G. Lacerda15Instituto de Pesquisas Clínicas Carlos Borborema, Fundação de Medicina Tropical Doutor HeitorGrupo de pesquisa em Biologia molecular e imunologia da Malária, Instituto René Rachou (IRR), FiocruzGrupo de pesquisa em Biologia molecular e imunologia da Malária, Instituto René Rachou (IRR), FiocruzLaboratório de Biologia da Conservação, Instituto de Ciências Biológicas, Projeto Sauim-de-Coleira, Universidade Federal do AmazonasInstituto de Pesquisas Clínicas Carlos Borborema, Fundação de Medicina Tropical Doutor HeitorInstituto de Pesquisas Clínicas Carlos Borborema, Fundação de Medicina Tropical Doutor HeitorInstituto de Pesquisas Clínicas Carlos Borborema, Fundação de Medicina Tropical Doutor HeitorInstituto de Pesquisas Clínicas Carlos Borborema, Fundação de Medicina Tropical Doutor HeitorInstituto de Pesquisas Clínicas Carlos Borborema, Fundação de Medicina Tropical Doutor HeitorInstituto de Pesquisas Clínicas Carlos Borborema, Fundação de Medicina Tropical Doutor HeitorInstituto de Pesquisas Clínicas Carlos Borborema, Fundação de Medicina Tropical Doutor HeitorInstituto de Pesquisas Clínicas Carlos Borborema, Fundação de Medicina Tropical Doutor HeitorDepartment of Pathology, Center for Biodefense and Emerging Infectious Diseases, Center for Tropical Diseases, Institute for Human Infection and Immunity, University of Texas Medical BranchGrupo de pesquisa em Biologia molecular e imunologia da Malária, Instituto René Rachou (IRR), FiocruzInstituto de Pesquisas Clínicas Carlos Borborema, Fundação de Medicina Tropical Doutor HeitorInstituto de Pesquisas Clínicas Carlos Borborema, Fundação de Medicina Tropical Doutor HeitorAbstract Background The groundwork for malaria elimination does not currently consider the potential of Plasmodium zoonotic cycles that involve non-human primates (NHPs) in sylvatic environments. Since vivax malaria is less responsive to control measures, finding Plasmodium vivax infected NHPs adds even more concern. Methods Both Free-living monkeys in forest fragments inside the urban area and captive monkeys from a local zoo had blood samples tested for Plasmodium species. Results In this study, among the Neotropical monkeys tested, three (4.4%), one captive and two free-living, were found to be naturally infected by P. vivax. Conclusion This important finding indicates that it is necessary to estimate the extent to which P. vivax NHP infection contributes to the maintenance of malaria transmission to humans. Therefore, the discussion on wildlife conservation and management must be incorporated into the malaria elimination agenda.https://doi.org/10.1186/s12936-022-04349-6Plasmodium vivaxMalariaZoonotic cycleMalaria eliminationNon-human primates |
| spellingShingle | Bárbara Aparecida Chaves Denise Anete Madureira de Alvarenga Matheus de Oliveira Costa Pereira Marcelo Gordo Emanuelle L. Da Silva Edson Rodrigues Costa Aline Souza de Menezes Medeiros Igor José Martins Pedrosa Daniela Brito Maurício Teixeira Lima Maria Paula Mourão Wuelton M. Monteiro Nikos Vasilakis Cristiana Ferreira Alves de Brito Gisely C. Melo Marcus V. G. Lacerda Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination? Malaria Journal Plasmodium vivax Malaria Zoonotic cycle Malaria elimination Non-human primates |
| title | Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination? |
| title_full | Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination? |
| title_fullStr | Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination? |
| title_full_unstemmed | Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination? |
| title_short | Is zoonotic Plasmodium vivax malaria an obstacle for disease elimination? |
| title_sort | is zoonotic plasmodium vivax malaria an obstacle for disease elimination |
| topic | Plasmodium vivax Malaria Zoonotic cycle Malaria elimination Non-human primates |
| url | https://doi.org/10.1186/s12936-022-04349-6 |
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