Clinical Results of Flow Diverter Treatments for Cerebral Aneurysms under Local Anesthesia
Flow diverters (FD) have become the mainstay for the endovascular treatment of unruptured intracranial aneurysms (UIA). Most FD procedures are performed under general anesthesia, and the influence of local anesthesia (LA) on outcomes remains unknown. This study evaluated the results of FD placement...
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MDPI AG
2022-08-01
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| Series: | Brain Sciences |
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| Online Access: | https://www.mdpi.com/2076-3425/12/8/1076 |
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| author | Saujanya Rajbhandari Hidetoshi Matsukawa Kazutaka Uchida Manabu Shirakawa Shinichi Yoshimura |
| author_facet | Saujanya Rajbhandari Hidetoshi Matsukawa Kazutaka Uchida Manabu Shirakawa Shinichi Yoshimura |
| author_sort | Saujanya Rajbhandari |
| collection | DOAJ |
| description | Flow diverters (FD) have become the mainstay for the endovascular treatment of unruptured intracranial aneurysms (UIA). Most FD procedures are performed under general anesthesia, and the influence of local anesthesia (LA) on outcomes remains unknown. This study evaluated the results of FD placement under LA. Data of patients treated for FD under LA between August 2016 and January 2022 were analyzed retrospectively. A good outcome was defined as a modified Rankin scale score of 0–2. Major stroke, steno-occlusive events of FD, mortality, and satisfactory aneurysm occlusion were also evaluated. In total, 169 patients undertook 182 treatments (139 [82%) female, mean age 61 ± 11 years). The median maximum aneurysm size was 9.5 mm (interquartile range 6.1-14 mm). A flow re-directed endoluminal device and pipeline embolization device were used in 103 (57%) and 78 (43%) treatments. One patient (0.59%) experienced major stroke, and steno-occlusive events were observed in four patients (2.4%). A good outcome at 90 days was obtained in 164 patients (98%), and one patient died (0.59% mortality). During the median follow-up period of 345 days (interquartile range 176–366 days), satisfactory aneurysm occlusion was observed in 126 of 160 aneurysms (79%). Our results suggest that FD placement under LA is a safe and effective treatment for UIA. |
| first_indexed | 2024-03-09T11:48:52Z |
| format | Article |
| id | doaj.art-d7448ac66c2d42bbae0b429d05ba60bb |
| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-03-09T11:48:52Z |
| publishDate | 2022-08-01 |
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| record_format | Article |
| series | Brain Sciences |
| spelling | doaj.art-d7448ac66c2d42bbae0b429d05ba60bb2023-11-30T23:18:23ZengMDPI AGBrain Sciences2076-34252022-08-01128107610.3390/brainsci12081076Clinical Results of Flow Diverter Treatments for Cerebral Aneurysms under Local AnesthesiaSaujanya Rajbhandari0Hidetoshi Matsukawa1Kazutaka Uchida2Manabu Shirakawa3Shinichi Yoshimura4Department of Neurosurgery, Hyogo College of Medicine, Nishinomiya 663-8501, Hyogo, JapanDepartment of Neurosurgery, Takarazuka City Hospital, Takarazuka 665-0827, Hyogo, JapanDepartment of Neurosurgery, Hyogo College of Medicine, Nishinomiya 663-8501, Hyogo, JapanDepartment of Neurosurgery, Hyogo College of Medicine, Nishinomiya 663-8501, Hyogo, JapanDepartment of Neurosurgery, Hyogo College of Medicine, Nishinomiya 663-8501, Hyogo, JapanFlow diverters (FD) have become the mainstay for the endovascular treatment of unruptured intracranial aneurysms (UIA). Most FD procedures are performed under general anesthesia, and the influence of local anesthesia (LA) on outcomes remains unknown. This study evaluated the results of FD placement under LA. Data of patients treated for FD under LA between August 2016 and January 2022 were analyzed retrospectively. A good outcome was defined as a modified Rankin scale score of 0–2. Major stroke, steno-occlusive events of FD, mortality, and satisfactory aneurysm occlusion were also evaluated. In total, 169 patients undertook 182 treatments (139 [82%) female, mean age 61 ± 11 years). The median maximum aneurysm size was 9.5 mm (interquartile range 6.1-14 mm). A flow re-directed endoluminal device and pipeline embolization device were used in 103 (57%) and 78 (43%) treatments. One patient (0.59%) experienced major stroke, and steno-occlusive events were observed in four patients (2.4%). A good outcome at 90 days was obtained in 164 patients (98%), and one patient died (0.59% mortality). During the median follow-up period of 345 days (interquartile range 176–366 days), satisfactory aneurysm occlusion was observed in 126 of 160 aneurysms (79%). Our results suggest that FD placement under LA is a safe and effective treatment for UIA.https://www.mdpi.com/2076-3425/12/8/1076anesthesiacerebral aneurysmflow diverteroutcome |
| spellingShingle | Saujanya Rajbhandari Hidetoshi Matsukawa Kazutaka Uchida Manabu Shirakawa Shinichi Yoshimura Clinical Results of Flow Diverter Treatments for Cerebral Aneurysms under Local Anesthesia Brain Sciences anesthesia cerebral aneurysm flow diverter outcome |
| title | Clinical Results of Flow Diverter Treatments for Cerebral Aneurysms under Local Anesthesia |
| title_full | Clinical Results of Flow Diverter Treatments for Cerebral Aneurysms under Local Anesthesia |
| title_fullStr | Clinical Results of Flow Diverter Treatments for Cerebral Aneurysms under Local Anesthesia |
| title_full_unstemmed | Clinical Results of Flow Diverter Treatments for Cerebral Aneurysms under Local Anesthesia |
| title_short | Clinical Results of Flow Diverter Treatments for Cerebral Aneurysms under Local Anesthesia |
| title_sort | clinical results of flow diverter treatments for cerebral aneurysms under local anesthesia |
| topic | anesthesia cerebral aneurysm flow diverter outcome |
| url | https://www.mdpi.com/2076-3425/12/8/1076 |
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