The Effects of Intrahippocampus Injection of Almond oil on Passive Avoidance Learning and Memory in Adult Male Rat
Abstract Background & aim: Almond oil contains compounds such asoleic acid, omega 3, 6, 9 polyunsaturated fatty acids and vitamin E. The aim of this study was to investigate the effects of intra-hippocampal injection of almond oil on passive avoidance learning and memory in male rats. Methods...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | fas |
| Published: |
Yasuj University Of Medical Sciences
2013-04-01
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| Series: | Armaghane Danesh Bimonthly Journal |
| Subjects: | |
| Online Access: | http://armaghanj.yums.ac.ir/browse.php?a_code=A-10-1-253&slc_lang=en&sid=1 |
| _version_ | 1818024654012416000 |
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| author | T Shahrivar AA Moazedi AA Rasekh S Almasi-Turk S Razmeh A Roozbehi |
| author_facet | T Shahrivar AA Moazedi AA Rasekh S Almasi-Turk S Razmeh A Roozbehi |
| author_sort | T Shahrivar |
| collection | DOAJ |
| description | Abstract
Background & aim: Almond oil contains compounds such asoleic acid, omega 3, 6, 9 polyunsaturated fatty acids and vitamin E. The aim of this study was to investigate the effects of intra-hippocampal injection of almond oil on passive avoidance learning and memory in male rats.
Methods: In this experimental study, 56 male rats were randomly divided into 8 groups, including a control, 3 sailin groups which received normal saline 0.5, 1, 2 µl and 4 peanut oil groups which received 5/0, 1, 5/1 and 2 µl of oil.All groups, except the control, Groups except the control group were cannulated with stereotaxic surgery in the left CA1 region. One week after recovery, all groups were trained by shuttle box. Immediately after training, different doses of almond oil and saline were injected through the cannula in CA1 of hippocampus. After 48 hours, their Passive avoidance memory and learning were evaluated. Data were analyzed by ANOVA.
Results: Almond oil doses of 0.5,1, 1.5 and 2 µg significantly improved passive avoidance learning and memory (P<0.05), but saline did not have.
Conclusion: Almond oil as a steroid, effects on learning and memory and can improve learning and memory.
Key Words: Learning, Memory, Almond oil, Hippocampus and Shuttle Box |
| first_indexed | 2024-12-10T04:03:39Z |
| format | Article |
| id | doaj.art-d745fd1c491742c79c6cb525c63f5fbb |
| institution | Directory Open Access Journal |
| issn | 1728-6506 1728-6514 |
| language | fas |
| last_indexed | 2024-12-10T04:03:39Z |
| publishDate | 2013-04-01 |
| publisher | Yasuj University Of Medical Sciences |
| record_format | Article |
| series | Armaghane Danesh Bimonthly Journal |
| spelling | doaj.art-d745fd1c491742c79c6cb525c63f5fbb2022-12-22T02:02:55ZfasYasuj University Of Medical SciencesArmaghane Danesh Bimonthly Journal1728-65061728-65142013-04-011815060The Effects of Intrahippocampus Injection of Almond oil on Passive Avoidance Learning and Memory in Adult Male RatT Shahrivar0AA Moazedi1AA Rasekh2S Almasi-Turk3S Razmeh4A Roozbehi5 Abstract Background & aim: Almond oil contains compounds such asoleic acid, omega 3, 6, 9 polyunsaturated fatty acids and vitamin E. The aim of this study was to investigate the effects of intra-hippocampal injection of almond oil on passive avoidance learning and memory in male rats. Methods: In this experimental study, 56 male rats were randomly divided into 8 groups, including a control, 3 sailin groups which received normal saline 0.5, 1, 2 µl and 4 peanut oil groups which received 5/0, 1, 5/1 and 2 µl of oil.All groups, except the control, Groups except the control group were cannulated with stereotaxic surgery in the left CA1 region. One week after recovery, all groups were trained by shuttle box. Immediately after training, different doses of almond oil and saline were injected through the cannula in CA1 of hippocampus. After 48 hours, their Passive avoidance memory and learning were evaluated. Data were analyzed by ANOVA. Results: Almond oil doses of 0.5,1, 1.5 and 2 µg significantly improved passive avoidance learning and memory (P<0.05), but saline did not have. Conclusion: Almond oil as a steroid, effects on learning and memory and can improve learning and memory. Key Words: Learning, Memory, Almond oil, Hippocampus and Shuttle Boxhttp://armaghanj.yums.ac.ir/browse.php?a_code=A-10-1-253&slc_lang=en&sid=1Key Words: Learning Memory Almond oil Hippocampus and Shuttle Box |
| spellingShingle | T Shahrivar AA Moazedi AA Rasekh S Almasi-Turk S Razmeh A Roozbehi The Effects of Intrahippocampus Injection of Almond oil on Passive Avoidance Learning and Memory in Adult Male Rat Armaghane Danesh Bimonthly Journal Key Words: Learning Memory Almond oil Hippocampus and Shuttle Box |
| title | The Effects of Intrahippocampus Injection of Almond oil on Passive Avoidance Learning and Memory in Adult Male Rat |
| title_full | The Effects of Intrahippocampus Injection of Almond oil on Passive Avoidance Learning and Memory in Adult Male Rat |
| title_fullStr | The Effects of Intrahippocampus Injection of Almond oil on Passive Avoidance Learning and Memory in Adult Male Rat |
| title_full_unstemmed | The Effects of Intrahippocampus Injection of Almond oil on Passive Avoidance Learning and Memory in Adult Male Rat |
| title_short | The Effects of Intrahippocampus Injection of Almond oil on Passive Avoidance Learning and Memory in Adult Male Rat |
| title_sort | effects of intrahippocampus injection of almond oil on passive avoidance learning and memory in adult male rat |
| topic | Key Words: Learning Memory Almond oil Hippocampus and Shuttle Box |
| url | http://armaghanj.yums.ac.ir/browse.php?a_code=A-10-1-253&slc_lang=en&sid=1 |
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