NKG2C+NKG2A− Natural Killer Cells are Associated with a Lower Viral Set Point and may Predict Disease Progression in Individuals with Primary HIV Infection

NKG2C+NKG2A− Natural Killer Cells are Associated with a Lower Viral Set Point and may Predict Disease Progression in Individuals with Primary HIV Infection

Natural killer (NK) cells are the first line of defense against pathogens of the immune system and also play an important role in resistance against HIV. The activating receptor NKG2C and the inhibitory receptor NKG2A co-modulate the function of NK cells by recognizing the same ligand, HLA-E. Howeve...

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Bibliographic Details
Main Authors: Meichen Ma, Zhuo Wang, Xi Chen, Anfu Tao, Lei He, Shuai Fu, Zining Zhang, Yajing Fu, Chenxi Guo, Jing Liu, Xiaoxu Han, Junjie Xu, Zhenxing Chu, Haibo Ding, Hong Shang, Yongjun Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Immunology
Subjects:
NKG2C
NKG2A
pHi
HIV
prediction
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01176/full

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