Gp350-anchored extracellular vesicles: promising vehicles for delivering therapeutic drugs of B cell malignancies

Gp350-anchored extracellular vesicles: promising vehicles for delivering therapeutic drugs of B cell malignancies

Although chimeric antigen receptor-modified (CAR) T cell therapy has been successfully applied in the treatment of acute B lymphocytic leukemia, its effect on Burkitt lymphoma (BL) and chronic B lymphocytic leukemia (B-CLL) is unsatisfactory. Moreover, fatal side effects greatly impede CAR T cell ap...

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Bibliographic Details
Main Authors: Huiqing Xiu, Xi Nan, Danfeng Guo, Jiaoli Wang, Jiahui Li, Yanmei Peng, Guirun Xiong, Shibo Wang, Changjun Wang, Gensheng Zhang, Yunshan Yang, Zhijian Cai
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Extracellular vesicles
Gp350
CD21
Red blood cells
B cell malignancies
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087622000423

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