Efficacy of cucurmin and aloevera extracts gel as local drugs delivery agents
Introduction: The usage of antimicrobials as local drug delivery (LDD) agents in the treatment of periodontitis has posed limitations due to the development of bacterial resistance, high cost, and unavailability, thus indicating the need for safer and economic alternatives. Methodology: A split-mout...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Journal of Pharmacy and Bioallied Sciences |
| Subjects: | |
| Online Access: | http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2023;volume=15;issue=6;spage=981;epage=983;aulast=Borgohain |
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| author | Raktapratim Borgohain Nikhat Fatima Hiroj Bagde Anishka Dhanai Koushik Mukherjee Prerna Joshi |
| author_facet | Raktapratim Borgohain Nikhat Fatima Hiroj Bagde Anishka Dhanai Koushik Mukherjee Prerna Joshi |
| author_sort | Raktapratim Borgohain |
| collection | DOAJ |
| description | Introduction: The usage of antimicrobials as local drug delivery (LDD) agents in the treatment of periodontitis has posed limitations due to the development of bacterial resistance, high cost, and unavailability, thus indicating the need for safer and economic alternatives. Methodology: A split-mouth randomized clinical trial was carried out on 10 patients. Three sites in different quadrants were assigned, treatment modality of scaling and root planing (SRP) alone, SRP with LDD of curcumin gel, and SRP with LDD of 99% pure aloe vera gel, respectively. Clinical parameters were recorded at baseline and on 30th day postoperatively. Results: Curcumin and aloe vera in addition to SRP demonstrated improvements in clinical parameters, though 99% aloe vera extract produced more statistically significant results when used as an LDD agent, as shown in intergroup comparisons for changes in periodontal parameters. Conclusion: Curcumin 10mg (Curenext) and 99% aloe vera extract as LDD along with regular mechanical debridement is a promising therapy in the treatment of chronic periodontitis. |
| first_indexed | 2024-03-12T13:44:30Z |
| format | Article |
| id | doaj.art-d74d7bd1728441edb658a37cceea94ff |
| institution | Directory Open Access Journal |
| issn | 0975-7406 |
| language | English |
| last_indexed | 2024-03-12T13:44:30Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Pharmacy and Bioallied Sciences |
| spelling | doaj.art-d74d7bd1728441edb658a37cceea94ff2023-08-23T09:45:23ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0975-74062023-01-0115698198310.4103/jpbs.jpbs_259_23Efficacy of cucurmin and aloevera extracts gel as local drugs delivery agentsRaktapratim BorgohainNikhat FatimaHiroj BagdeAnishka DhanaiKoushik MukherjeePrerna JoshiIntroduction: The usage of antimicrobials as local drug delivery (LDD) agents in the treatment of periodontitis has posed limitations due to the development of bacterial resistance, high cost, and unavailability, thus indicating the need for safer and economic alternatives. Methodology: A split-mouth randomized clinical trial was carried out on 10 patients. Three sites in different quadrants were assigned, treatment modality of scaling and root planing (SRP) alone, SRP with LDD of curcumin gel, and SRP with LDD of 99% pure aloe vera gel, respectively. Clinical parameters were recorded at baseline and on 30th day postoperatively. Results: Curcumin and aloe vera in addition to SRP demonstrated improvements in clinical parameters, though 99% aloe vera extract produced more statistically significant results when used as an LDD agent, as shown in intergroup comparisons for changes in periodontal parameters. Conclusion: Curcumin 10mg (Curenext) and 99% aloe vera extract as LDD along with regular mechanical debridement is a promising therapy in the treatment of chronic periodontitis.http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2023;volume=15;issue=6;spage=981;epage=983;aulast=Borgohainchronic periodontitiscurcuminlddscalingand root planing |
| spellingShingle | Raktapratim Borgohain Nikhat Fatima Hiroj Bagde Anishka Dhanai Koushik Mukherjee Prerna Joshi Efficacy of cucurmin and aloevera extracts gel as local drugs delivery agents Journal of Pharmacy and Bioallied Sciences chronic periodontitis curcumin ldd scaling and root planing |
| title | Efficacy of cucurmin and aloevera extracts gel as local drugs delivery agents |
| title_full | Efficacy of cucurmin and aloevera extracts gel as local drugs delivery agents |
| title_fullStr | Efficacy of cucurmin and aloevera extracts gel as local drugs delivery agents |
| title_full_unstemmed | Efficacy of cucurmin and aloevera extracts gel as local drugs delivery agents |
| title_short | Efficacy of cucurmin and aloevera extracts gel as local drugs delivery agents |
| title_sort | efficacy of cucurmin and aloevera extracts gel as local drugs delivery agents |
| topic | chronic periodontitis curcumin ldd scaling and root planing |
| url | http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2023;volume=15;issue=6;spage=981;epage=983;aulast=Borgohain |
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