A Study on Allergic responses Between Bee Venom and Sweet Bee Venom Pharmacopuncture
Objectives : Sweet bee venom is made by removing allergen from the bee venom through gel filtration chromatography and propionic acid/urea polyacrylamide gel electrophoresis. The aim of this study was to verify allergy inhibitory action in Sweet Bee Venom in which the allergy causing enzyme is remov...
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| Format: | Article |
| Language: | English |
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Korean Pharmacopuncture Institute
2006-12-01
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| Series: | Journal of Pharmacopuncture |
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| Online Access: | http://dx.doi.org/10.3831/KPI.2006.9.3.061 |
| _version_ | 1818765359985983488 |
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| author | Jin Seon Lee Jong Young Lee Ki Rok Kwon Hee Choon Lee |
| author_facet | Jin Seon Lee Jong Young Lee Ki Rok Kwon Hee Choon Lee |
| author_sort | Jin Seon Lee |
| collection | DOAJ |
| description | Objectives : Sweet bee venom is made by removing allergen from the bee venom through gel filtration chromatography and propionic acid/urea polyacrylamide gel electrophoresis. The aim of this study was to verify allergy inhibitory action in Sweet Bee Venom in which the allergy causing enzyme is removed.
Methods : 95 healthy adult men and women were selected through a survey whom had never received the bee venom therapy in the past. The concentration of bee venom pharmacopuncture and Sweet BV pharmacopuncture was equally at 0.1mg/㎖ and the experiment was conducted as the double blind test. Experiment groups were classified into low dosage groups (0.1㎖ for both bee venom pharmacopuncture and Sweet BV) and high dosage groups where 0.4㎖ of respective administrations were rendered made observations for allergic responses.
Results : Participants of the study was comprised of 71 men and 24 women with the average age of 29.0 years. According to results of the low dosage groups, Sweet BV group showed significant reduction in pain after 4 hours and 24 hours compared to the bee venom pharmacopuncture group. Other allergic responses were insignificant between the groups. For the high dosage groups, Sweet bee venom group showed reduction in pain after 30 minutes and 4 hours. Other allergic responses such as edema, itchiness, dizziness from hypersensitivity, and fatigue were significantly lower in the Sweet bee venom administered group after 30 minutes.
Conclusions : As a result of removed allergen, Sweet bee venom significantly inhibits allergic responses both locally and throughout the body. This indicates wider and easier application of Sweet bee venom for the symptoms applicable to the bee venom pharmacopuncture. Further comparative studies should be conducted to yield more objective verification. |
| first_indexed | 2024-12-18T08:16:51Z |
| format | Article |
| id | doaj.art-d74fb58cba78465ebb3afc46db0dcb83 |
| institution | Directory Open Access Journal |
| issn | 2093-6966 2234-6856 |
| language | English |
| last_indexed | 2024-12-18T08:16:51Z |
| publishDate | 2006-12-01 |
| publisher | Korean Pharmacopuncture Institute |
| record_format | Article |
| series | Journal of Pharmacopuncture |
| spelling | doaj.art-d74fb58cba78465ebb3afc46db0dcb832022-12-21T21:14:48ZengKorean Pharmacopuncture InstituteJournal of Pharmacopuncture2093-69662234-68562006-12-0193617710.3831/KPI.2006.9.3.061 A Study on Allergic responses Between Bee Venom and Sweet Bee Venom PharmacopunctureJin Seon Lee0Jong Young Lee1Ki Rok Kwon2Hee Choon Lee3Dept. of Acupuncture & Moxibustion, Oriental Medical College, Sangji UniversityDept. of Acupuncture & Moxibustion, Oriental Medical College, Sangji UniversityDept. of Acupuncture & Moxibustion, Oriental Medical College, Sangji UniversityDept. of Statistics, Sangji UniversityObjectives : Sweet bee venom is made by removing allergen from the bee venom through gel filtration chromatography and propionic acid/urea polyacrylamide gel electrophoresis. The aim of this study was to verify allergy inhibitory action in Sweet Bee Venom in which the allergy causing enzyme is removed. Methods : 95 healthy adult men and women were selected through a survey whom had never received the bee venom therapy in the past. The concentration of bee venom pharmacopuncture and Sweet BV pharmacopuncture was equally at 0.1mg/㎖ and the experiment was conducted as the double blind test. Experiment groups were classified into low dosage groups (0.1㎖ for both bee venom pharmacopuncture and Sweet BV) and high dosage groups where 0.4㎖ of respective administrations were rendered made observations for allergic responses. Results : Participants of the study was comprised of 71 men and 24 women with the average age of 29.0 years. According to results of the low dosage groups, Sweet BV group showed significant reduction in pain after 4 hours and 24 hours compared to the bee venom pharmacopuncture group. Other allergic responses were insignificant between the groups. For the high dosage groups, Sweet bee venom group showed reduction in pain after 30 minutes and 4 hours. Other allergic responses such as edema, itchiness, dizziness from hypersensitivity, and fatigue were significantly lower in the Sweet bee venom administered group after 30 minutes. Conclusions : As a result of removed allergen, Sweet bee venom significantly inhibits allergic responses both locally and throughout the body. This indicates wider and easier application of Sweet bee venom for the symptoms applicable to the bee venom pharmacopuncture. Further comparative studies should be conducted to yield more objective verification.http://dx.doi.org/10.3831/KPI.2006.9.3.061Bee VenomSweet Bee Venomdouble blind testallergy response |
| spellingShingle | Jin Seon Lee Jong Young Lee Ki Rok Kwon Hee Choon Lee A Study on Allergic responses Between Bee Venom and Sweet Bee Venom Pharmacopuncture Journal of Pharmacopuncture Bee Venom Sweet Bee Venom double blind test allergy response |
| title | A Study on Allergic responses Between Bee Venom and Sweet Bee Venom Pharmacopuncture |
| title_full | A Study on Allergic responses Between Bee Venom and Sweet Bee Venom Pharmacopuncture |
| title_fullStr | A Study on Allergic responses Between Bee Venom and Sweet Bee Venom Pharmacopuncture |
| title_full_unstemmed | A Study on Allergic responses Between Bee Venom and Sweet Bee Venom Pharmacopuncture |
| title_short | A Study on Allergic responses Between Bee Venom and Sweet Bee Venom Pharmacopuncture |
| title_sort | study on allergic responses between bee venom and sweet bee venom pharmacopuncture |
| topic | Bee Venom Sweet Bee Venom double blind test allergy response |
| url | http://dx.doi.org/10.3831/KPI.2006.9.3.061 |
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