E, K, B5, B6, and B9 vitamins and their specific immunological effects evaluated by flow cytometry

It has been proven that vitamins play an essential role in preventing certain diseases since ancient times. It is thus fruitless to approach the roles of vitamins without making reference to the techniques used in evaluating the effects of these micronutrients. Therefore, the aim of this paper was t...

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Main Authors: Camelia Munteanu, Ioana Berindean, Mihaela Mihai, Bianca Pop, Mihai Popa, Leon Muntean, Olivia Petrescu, Andreea Ona
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.1089476/full
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author Camelia Munteanu
Ioana Berindean
Mihaela Mihai
Bianca Pop
Mihai Popa
Leon Muntean
Olivia Petrescu
Andreea Ona
author_facet Camelia Munteanu
Ioana Berindean
Mihaela Mihai
Bianca Pop
Mihai Popa
Leon Muntean
Olivia Petrescu
Andreea Ona
author_sort Camelia Munteanu
collection DOAJ
description It has been proven that vitamins play an essential role in preventing certain diseases since ancient times. It is thus fruitless to approach the roles of vitamins without making reference to the techniques used in evaluating the effects of these micronutrients. Therefore, the aim of this paper was to summarize the immunological effects of E, K, B5, B6, and B9 vitamins evaluated by flow cytometry. Some of these significant effects were presented and discussed: (a) The role of vitamins E in the prevention and treatment of different types of cancer. (b) The properties of K vitamins in the development and maintenance of pheochromocytoma Cell Line 12 (PC12) cells in Parkinson’s disease; (c) The improvement effect of vitamin B5 on the loss of bone mass in low estrogen conditions; (d) The anticancer role of vitamins B6. (e) The role of Vitamin B9 in the regulation of Treg cells. As such, the flow cytometry technique used to assess these properties is essential to evaluate the immunomodulatory effects of certain vitamins. The technique undergoes constant improvement which makes it possible to determine several parameters with a role in the modulation of the immune function and at the same time increase the accuracy of the methods that highlight them.
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spelling doaj.art-d754d97ff98a4ec180df07ff2075d69f2023-01-05T13:27:22ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2023-01-01910.3389/fmed.2022.10894761089476E, K, B5, B6, and B9 vitamins and their specific immunological effects evaluated by flow cytometryCamelia Munteanu0Ioana Berindean1Mihaela Mihai2Bianca Pop3Mihai Popa4Leon Muntean5Olivia Petrescu6Andreea Ona7Department of Plant Culture, Faculty of Agriculture, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, RomaniaDepartment of Plant Culture, Faculty of Agriculture, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, RomaniaDepartment of Transversal Competencies, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, RomaniaDepartment of Plant Culture, Faculty of Agriculture, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, RomaniaDepartment of Plant Culture, Faculty of Agriculture, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, RomaniaDepartment of Plant Culture, Faculty of Agriculture, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, RomaniaDepartment of Applied Modern Languages, Faculty of Letters, Babeş-Bolyai University, Cluj-Napoca, RomaniaDepartment of Plant Culture, Faculty of Agriculture, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, RomaniaIt has been proven that vitamins play an essential role in preventing certain diseases since ancient times. It is thus fruitless to approach the roles of vitamins without making reference to the techniques used in evaluating the effects of these micronutrients. Therefore, the aim of this paper was to summarize the immunological effects of E, K, B5, B6, and B9 vitamins evaluated by flow cytometry. Some of these significant effects were presented and discussed: (a) The role of vitamins E in the prevention and treatment of different types of cancer. (b) The properties of K vitamins in the development and maintenance of pheochromocytoma Cell Line 12 (PC12) cells in Parkinson’s disease; (c) The improvement effect of vitamin B5 on the loss of bone mass in low estrogen conditions; (d) The anticancer role of vitamins B6. (e) The role of Vitamin B9 in the regulation of Treg cells. As such, the flow cytometry technique used to assess these properties is essential to evaluate the immunomodulatory effects of certain vitamins. The technique undergoes constant improvement which makes it possible to determine several parameters with a role in the modulation of the immune function and at the same time increase the accuracy of the methods that highlight them.https://www.frontiersin.org/articles/10.3389/fmed.2022.1089476/fullanticancerdiseasesflow cytometryimmunologyvitamins
spellingShingle Camelia Munteanu
Ioana Berindean
Mihaela Mihai
Bianca Pop
Mihai Popa
Leon Muntean
Olivia Petrescu
Andreea Ona
E, K, B5, B6, and B9 vitamins and their specific immunological effects evaluated by flow cytometry
Frontiers in Medicine
anticancer
diseases
flow cytometry
immunology
vitamins
title E, K, B5, B6, and B9 vitamins and their specific immunological effects evaluated by flow cytometry
title_full E, K, B5, B6, and B9 vitamins and their specific immunological effects evaluated by flow cytometry
title_fullStr E, K, B5, B6, and B9 vitamins and their specific immunological effects evaluated by flow cytometry
title_full_unstemmed E, K, B5, B6, and B9 vitamins and their specific immunological effects evaluated by flow cytometry
title_short E, K, B5, B6, and B9 vitamins and their specific immunological effects evaluated by flow cytometry
title_sort e k b5 b6 and b9 vitamins and their specific immunological effects evaluated by flow cytometry
topic anticancer
diseases
flow cytometry
immunology
vitamins
url https://www.frontiersin.org/articles/10.3389/fmed.2022.1089476/full
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