Tissue inhibitor of matrix metalloproteinase-1 mediates erythropoietin-induced neuroprotection in hypoxia ischemia

Tissue inhibitor of matrix metalloproteinase-1 mediates erythropoietin-induced neuroprotection in hypoxia ischemia

Previous studies have shown that erythropoietin (EPO) is neuroprotective in both in vivo and in vitro models of hypoxia ischemia. However these studies hold limited clinical translations because the underlying mechanism remains unclear and the key molecules involved in EPO-induced neuroprotection ar...

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Bibliographic Details
Main Authors: Rhonda Souvenir, Nancy Fathali, Robert P. Ostrowski, Tim Lekic, John H. Zhang, Jiping Tang
Format: Article
Language:English
Published: Elsevier 2011-10-01
Series:Neurobiology of Disease
Subjects:
JAK-2
STAT-3
TIMP-1
EPO
Neonatal HI
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996111001896

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