Allopregnanolone pleiotropic action in neurons and astrocytes: calcium signaling as a unifying mechanism

Allopregnanolone pleiotropic action in neurons and astrocytes: calcium signaling as a unifying mechanism

ObjectiveAllopregnanolone (Allo) is a neurosteroid with pleiotropic action in the brain that includes neurogenesis, oligogenesis, human and rodent neural stem cell regeneration, increased glucose metabolism, mitochondrial respiration and biogenesis, improved cognitive function, and reduction of both...

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Bibliographic Details
Main Authors: Tian Wang, Shuhua Chen, Zisu Mao, Yuan Shang, Roberta Diaz Brinton
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Endocrinology
Subjects:
allopregnanolone
calcium signaling
mitochondria
neuroplasticity
astrocytic function
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1286931/full

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