Targeting Mitochondria by SS-31 Ameliorates the Whole Body Energy Status in Cancer- and Chemotherapy-Induced Cachexia

Targeting Mitochondria by SS-31 Ameliorates the Whole Body Energy Status in Cancer- and Chemotherapy-Induced Cachexia

<i>Objective</i>: Cachexia is a complex metabolic syndrome frequently occurring in cancer patients and exacerbated by chemotherapy. In skeletal muscle of cancer hosts, reduced oxidative capacity and low intracellular ATP resulting from abnormal mitochondrial function were described. <...

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Bibliographic Details
Main Authors: Riccardo Ballarò, Patrizia Lopalco, Valentina Audrito, Marc Beltrà, Fabrizio Pin, Roberto Angelini, Paola Costelli, Angela Corcelli, Andrea Bonetto, Hazel H. Szeto, Thomas M. O’Connell, Fabio Penna
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
cancer cachexia
muscle wasting
mitochondria
SS-31
metabolomics
liver
Online Access:https://www.mdpi.com/2072-6694/13/4/850

Internet

https://www.mdpi.com/2072-6694/13/4/850

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