Co-infection with Schistosoma haematobium and soil-transmitted helminths in rural South Africa
Schistosomiasis and soil-transmitted helminthiasis are among the most prevalent neglected tropical diseases and may lead to severe consequences. We assessed the extent of co-infection between Schistosoma haematobium and the soil-transmitted helminths (STHs) Ascaris lumbricoides and Trichuris trichiu...
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| Format: | Article |
| Language: | English |
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Academy of Science of South Africa
2017-03-01
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| Series: | South African Journal of Science |
| Subjects: | |
| Online Access: | https://www.sajs.co.za/article/view/3735 |
| _version_ | 1811234061141671936 |
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| author | Mari Molvik Elin Helland Siphosenkosi G. Zulu Elisabeth Kleppa Kristine Lillebo Svein G. Gundersen Jane D. Kvalsvig Myra Taylor Eyrun F. Kjetland Birgitte J. Vennervald |
| author_facet | Mari Molvik Elin Helland Siphosenkosi G. Zulu Elisabeth Kleppa Kristine Lillebo Svein G. Gundersen Jane D. Kvalsvig Myra Taylor Eyrun F. Kjetland Birgitte J. Vennervald |
| author_sort | Mari Molvik |
| collection | DOAJ |
| description | Schistosomiasis and soil-transmitted helminthiasis are among the most prevalent neglected tropical diseases and may lead to severe consequences. We assessed the extent of co-infection between Schistosoma haematobium and the soil-transmitted helminths (STHs) Ascaris lumbricoides and Trichuris trichiura in schoolgirls in the rural areas of KwaZulu-Natal, South Africa. We also explored if S. haematobium can serve as a predictor for soil-transmitted helminths in this area. From 15 selected schools, 726 primary schoolgirls aged 10–12 years provided both urine and stool samples. The samples were examined for the presence of eggs using the urine sedimentation technique for S. haematobium and the Kato Katz technique for STHs. Pearson’s chi-square test was used to calculate the association and Spearman’s rank correlation was used for the correlation analysis. There was a highly significant correlation between S. haematobium and STHs at a school level (Spearman’s correlation coefficient =0.93; p<0.001). The prevalences were found to be 36.9% and 38.8% for S. haematobium and STHs, respectively. A significant association was found between S. haematobium and STHs (odds ratio =2.05; confidence interval =1.58–2.93; p<0.001). Indirect indicators of urogenital schistosomiasis (e.g. water contact and haematuria) were significantly associated with A. lumbricoides and T. trichiura infection. We have demonstrated a highly significant correlation and overall association between urogenital schistosomiasis and A. lumbricoides and T. trichiura. We cautiously suggest that all S. haematobium endemic areas should be treated for STH infections.
Significance:
• The prevalences of urogenital schistosomiasis and soil-transmitted helminth infections were highly significantly correlated.
• More than half (60%) of the investigated schools are in need of annual treatment for S. haematobium infection.
• Almost half of the infected schoolgirls had a heavy intensity of S. haematobium infection.
• Nearly all the schools investigated require treatment for soil-transmitted helminthiasis once or even twice per year.
• This study can contribute to the epidemiological planning process of the deworming programme. |
| first_indexed | 2024-04-12T11:30:16Z |
| format | Article |
| id | doaj.art-d757112242d04903a914ea35537c6a89 |
| institution | Directory Open Access Journal |
| issn | 1996-7489 |
| language | English |
| last_indexed | 2024-04-12T11:30:16Z |
| publishDate | 2017-03-01 |
| publisher | Academy of Science of South Africa |
| record_format | Article |
| series | South African Journal of Science |
| spelling | doaj.art-d757112242d04903a914ea35537c6a892022-12-22T03:35:04ZengAcademy of Science of South AfricaSouth African Journal of Science1996-74892017-03-011133/46610.17159/sajs.2017/201602513735Co-infection with Schistosoma haematobium and soil-transmitted helminths in rural South AfricaMari Molvik0Elin Helland1Siphosenkosi G. Zulu2Elisabeth Kleppa3Kristine Lillebo4Svein G. Gundersen5Jane D. Kvalsvig6Myra Taylor7Eyrun F. Kjetland8Birgitte J. Vennervald91 Parasitology and Aquatic Diseases, University of Copenhagen, Copenhagen, Denmark 2 Norwegian Centre for Imported and Tropical Diseases, Department of Infectious Diseases Ullevaal, Oslo University Hospital, Oslo, NorwayParasitology and Aquatic Diseases, University of Copenhagen, Copenhagen, DenmarkDiscipline of Public Health Medicine, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa1 Norwegian Centre for Imported and Tropical Diseases, Department of Infectious Diseases Ullevaal, Oslo University Hospital, Oslo, Norway 2 Faculty of Medicine, University of Oslo, Oslo, NorwayNorwegian Centre for Imported and Tropical Diseases, Department of Infectious Diseases Ullevaal, Oslo University Hospital, Oslo, Norway1 Research Department, Sorlandet Hospital, Kristiansand, Norway 2 Institute for Global Development and Planning, University of Agder, Kristiansand, NorwayDiscipline of Public Health Medicine, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South AfricaDiscipline of Public Health Medicine, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa2 Norwegian Centre for Imported and Tropical Diseases, Department of Infectious Diseases Ullevaal, Oslo University Hospital, Oslo, Norway 3 Discipline of Public Health Medicine, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South AfricaParasitology and Aquatic Diseases, University of Copenhagen, Copenhagen, DenmarkSchistosomiasis and soil-transmitted helminthiasis are among the most prevalent neglected tropical diseases and may lead to severe consequences. We assessed the extent of co-infection between Schistosoma haematobium and the soil-transmitted helminths (STHs) Ascaris lumbricoides and Trichuris trichiura in schoolgirls in the rural areas of KwaZulu-Natal, South Africa. We also explored if S. haematobium can serve as a predictor for soil-transmitted helminths in this area. From 15 selected schools, 726 primary schoolgirls aged 10–12 years provided both urine and stool samples. The samples were examined for the presence of eggs using the urine sedimentation technique for S. haematobium and the Kato Katz technique for STHs. Pearson’s chi-square test was used to calculate the association and Spearman’s rank correlation was used for the correlation analysis. There was a highly significant correlation between S. haematobium and STHs at a school level (Spearman’s correlation coefficient =0.93; p<0.001). The prevalences were found to be 36.9% and 38.8% for S. haematobium and STHs, respectively. A significant association was found between S. haematobium and STHs (odds ratio =2.05; confidence interval =1.58–2.93; p<0.001). Indirect indicators of urogenital schistosomiasis (e.g. water contact and haematuria) were significantly associated with A. lumbricoides and T. trichiura infection. We have demonstrated a highly significant correlation and overall association between urogenital schistosomiasis and A. lumbricoides and T. trichiura. We cautiously suggest that all S. haematobium endemic areas should be treated for STH infections. Significance: • The prevalences of urogenital schistosomiasis and soil-transmitted helminth infections were highly significantly correlated. • More than half (60%) of the investigated schools are in need of annual treatment for S. haematobium infection. • Almost half of the infected schoolgirls had a heavy intensity of S. haematobium infection. • Nearly all the schools investigated require treatment for soil-transmitted helminthiasis once or even twice per year. • This study can contribute to the epidemiological planning process of the deworming programme.https://www.sajs.co.za/article/view/3735urogenital schistosomiasisKwaZulu-NatalAscaris lumbricoidesTrichuris trichiuraschoolchildren |
| spellingShingle | Mari Molvik Elin Helland Siphosenkosi G. Zulu Elisabeth Kleppa Kristine Lillebo Svein G. Gundersen Jane D. Kvalsvig Myra Taylor Eyrun F. Kjetland Birgitte J. Vennervald Co-infection with Schistosoma haematobium and soil-transmitted helminths in rural South Africa South African Journal of Science urogenital schistosomiasis KwaZulu-Natal Ascaris lumbricoides Trichuris trichiura schoolchildren |
| title | Co-infection with Schistosoma haematobium and soil-transmitted helminths in rural South Africa |
| title_full | Co-infection with Schistosoma haematobium and soil-transmitted helminths in rural South Africa |
| title_fullStr | Co-infection with Schistosoma haematobium and soil-transmitted helminths in rural South Africa |
| title_full_unstemmed | Co-infection with Schistosoma haematobium and soil-transmitted helminths in rural South Africa |
| title_short | Co-infection with Schistosoma haematobium and soil-transmitted helminths in rural South Africa |
| title_sort | co infection with schistosoma haematobium and soil transmitted helminths in rural south africa |
| topic | urogenital schistosomiasis KwaZulu-Natal Ascaris lumbricoides Trichuris trichiura schoolchildren |
| url | https://www.sajs.co.za/article/view/3735 |
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