Determinants of drug-related problems among ambulatory type 2 diabetes patients with hypertension comorbidity in Southwest Ethiopia: a prospective cross sectional study
Abstract Objective The aim of this study was to assess drug-related problems and its determinants in type 2 diabetes patients with hypertension co-morbidity. Results A total of 300 type 2 diabetes patients with hypertension co-morbidity were studied. The majority of participants, 194 (64.7%), were m...
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| Format: | Article |
| Language: | English |
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BMC
2018-09-01
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| Series: | BMC Research Notes |
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| Online Access: | http://link.springer.com/article/10.1186/s13104-018-3785-8 |
| _version_ | 1818247513833996288 |
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| author | Mohammed Yimama Habtemu Jarso Tigestu Alemu Desse |
| author_facet | Mohammed Yimama Habtemu Jarso Tigestu Alemu Desse |
| author_sort | Mohammed Yimama |
| collection | DOAJ |
| description | Abstract Objective The aim of this study was to assess drug-related problems and its determinants in type 2 diabetes patients with hypertension co-morbidity. Results A total of 300 type 2 diabetes patients with hypertension co-morbidity were studied. The majority of participants, 194 (64.7%), were males. Mean age of the participants was 54.44 ± 11.68 years. The mean durations of diabetes and hypertension were 5.37 ± 4.79 and 5.15 ± 4.65 years respectively. The most commonly prescribed antidiabetic medications were metformin in 200 (66.7%) and insulin 126 (42%) of the participants. Enalapril was the most commonly prescribed antihypertensive medication; 272 (90.7%). Aspirin was prescribed to 182 (60.7%) participants. Statins were prescribed to one-third (65.67%) of the participants. Eighty-five (28.3%) participants had diabetes related complications other than hypertension. A total of 494 drug related problems were identified. The mean number of drug related problems was 1.65 ± 1.05. The most common drug related problems were need for additional drug therapy (29.35%), ineffective drug (27.94%) and dose too low (15.8%). Independent predictors of drug related problems were age 41–60 years (AOR = 6.87, 95% CI 2.63–17.93), age > 60 years (AOR = 5.85, 95% CI 2.15–15.93) and the presence of comorbidity (AOR = 3.0, 95% CI 1.11–8.16). |
| first_indexed | 2024-12-12T15:05:54Z |
| format | Article |
| id | doaj.art-d759d68418424841915e00ce446d63db |
| institution | Directory Open Access Journal |
| issn | 1756-0500 |
| language | English |
| last_indexed | 2024-12-12T15:05:54Z |
| publishDate | 2018-09-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Research Notes |
| spelling | doaj.art-d759d68418424841915e00ce446d63db2022-12-22T00:20:44ZengBMCBMC Research Notes1756-05002018-09-011111610.1186/s13104-018-3785-8Determinants of drug-related problems among ambulatory type 2 diabetes patients with hypertension comorbidity in Southwest Ethiopia: a prospective cross sectional studyMohammed Yimama0Habtemu Jarso1Tigestu Alemu Desse2Department of Pharmacy, College of Health Sciences, Mizan Tepi UniversityDepartment of Epidemiology, College of Health Sciences, Jimma UniversityDepartment of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa UniversityAbstract Objective The aim of this study was to assess drug-related problems and its determinants in type 2 diabetes patients with hypertension co-morbidity. Results A total of 300 type 2 diabetes patients with hypertension co-morbidity were studied. The majority of participants, 194 (64.7%), were males. Mean age of the participants was 54.44 ± 11.68 years. The mean durations of diabetes and hypertension were 5.37 ± 4.79 and 5.15 ± 4.65 years respectively. The most commonly prescribed antidiabetic medications were metformin in 200 (66.7%) and insulin 126 (42%) of the participants. Enalapril was the most commonly prescribed antihypertensive medication; 272 (90.7%). Aspirin was prescribed to 182 (60.7%) participants. Statins were prescribed to one-third (65.67%) of the participants. Eighty-five (28.3%) participants had diabetes related complications other than hypertension. A total of 494 drug related problems were identified. The mean number of drug related problems was 1.65 ± 1.05. The most common drug related problems were need for additional drug therapy (29.35%), ineffective drug (27.94%) and dose too low (15.8%). Independent predictors of drug related problems were age 41–60 years (AOR = 6.87, 95% CI 2.63–17.93), age > 60 years (AOR = 5.85, 95% CI 2.15–15.93) and the presence of comorbidity (AOR = 3.0, 95% CI 1.11–8.16).http://link.springer.com/article/10.1186/s13104-018-3785-8Type 2 diabetesHypertensionDrug-related problemsEthiopia |
| spellingShingle | Mohammed Yimama Habtemu Jarso Tigestu Alemu Desse Determinants of drug-related problems among ambulatory type 2 diabetes patients with hypertension comorbidity in Southwest Ethiopia: a prospective cross sectional study BMC Research Notes Type 2 diabetes Hypertension Drug-related problems Ethiopia |
| title | Determinants of drug-related problems among ambulatory type 2 diabetes patients with hypertension comorbidity in Southwest Ethiopia: a prospective cross sectional study |
| title_full | Determinants of drug-related problems among ambulatory type 2 diabetes patients with hypertension comorbidity in Southwest Ethiopia: a prospective cross sectional study |
| title_fullStr | Determinants of drug-related problems among ambulatory type 2 diabetes patients with hypertension comorbidity in Southwest Ethiopia: a prospective cross sectional study |
| title_full_unstemmed | Determinants of drug-related problems among ambulatory type 2 diabetes patients with hypertension comorbidity in Southwest Ethiopia: a prospective cross sectional study |
| title_short | Determinants of drug-related problems among ambulatory type 2 diabetes patients with hypertension comorbidity in Southwest Ethiopia: a prospective cross sectional study |
| title_sort | determinants of drug related problems among ambulatory type 2 diabetes patients with hypertension comorbidity in southwest ethiopia a prospective cross sectional study |
| topic | Type 2 diabetes Hypertension Drug-related problems Ethiopia |
| url | http://link.springer.com/article/10.1186/s13104-018-3785-8 |
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