Limb salvage surgery without radiation therapy for soft tissue sarcomas of the foot
Combined limb salvage surgery and radiation therapy has been gaining traction for the treatment of soft tissue sarcomas of the foot in recent years. However, limb salvage surgery without radiation therapy is more desirable. In this study, we obtained good results from limb salvage surgery without ra...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-01-01
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| Series: | Foot & Ankle Surgery: Techniques, Reports & Cases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667396721000975 |
| _version_ | 1811333917018423296 |
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| author | Keiko Hayakawa Seiichi Matsumoto Keisuke Ae Taisuke Tanizawa Yuki Funauchi Yusuke Minami Masanori Saito |
| author_facet | Keiko Hayakawa Seiichi Matsumoto Keisuke Ae Taisuke Tanizawa Yuki Funauchi Yusuke Minami Masanori Saito |
| author_sort | Keiko Hayakawa |
| collection | DOAJ |
| description | Combined limb salvage surgery and radiation therapy has been gaining traction for the treatment of soft tissue sarcomas of the foot in recent years. However, limb salvage surgery without radiation therapy is more desirable. In this study, we obtained good results from limb salvage surgery without radiation therapy in soft tissue sarcoma of the foot. Twenty patients histologically diagnosed with soft tissue sarcoma who underwent limb salvage surgery, including ray amputation, were evaluated. Their mean age was 39 years. The mean follow-up period was 94.5 months (6–355 months). The histological diagnoses included 9 cases of synovial sarcoma. Treatment, local recurrence rate, survival rate, complication, and ADL were evaluated. Surgical procedures consisted of ray amputation in 5 cases and limb salvage surgery in 15. Of these 15 cases, 14 (93%) required reconstructive surgery for skin defects. One patient (5%) exhibited recurrence. The 5-year overall survival rate was 94.7%, and the 5-year local progression-free survival rate was 92.9%. Early postoperative complications were found in 5 of 20 cases (25%), comprising flap failure in 4 cases and infection in 1 case; however, all patients eventually demonstrated good functional outcomes. In this study, the recurrence rate was 5% for patients who underwent limb salvage surgery without radiation therapy, and we obtained good local control. Since the anatomical structures of the foot act as barriers to tumor progression, the use of a method of evaluating resection margins to determine the extent of resection enabled successful surgery, not combined with radiation, without the recurrence of sarcomas. |
| first_indexed | 2024-04-13T16:58:59Z |
| format | Article |
| id | doaj.art-d75ce7e7970a49a7906bd36ab1d2d87c |
| institution | Directory Open Access Journal |
| issn | 2667-3967 |
| language | English |
| last_indexed | 2024-04-13T16:58:59Z |
| publishDate | 2021-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Foot & Ankle Surgery: Techniques, Reports & Cases |
| spelling | doaj.art-d75ce7e7970a49a7906bd36ab1d2d87c2022-12-22T02:38:43ZengElsevierFoot & Ankle Surgery: Techniques, Reports & Cases2667-39672021-01-0114100096Limb salvage surgery without radiation therapy for soft tissue sarcomas of the footKeiko Hayakawa0Seiichi Matsumoto1Keisuke Ae2Taisuke Tanizawa3Yuki Funauchi4Yusuke Minami5Masanori Saito6Correspondence author at: Department of Orthopedic Oncology, Cancer Institute Hospital of the Japanese Foundation for Cancer Research, 3-8-31, Ariake, Koto-ku Tokyo, Japan.; Department of Orthopedic Oncology, Cancer Institute Hospital of the Japanese Foundation for Cancer Research, Tokyo, JapanDepartment of Orthopedic Oncology, Cancer Institute Hospital of the Japanese Foundation for Cancer Research, Tokyo, JapanDepartment of Orthopedic Oncology, Cancer Institute Hospital of the Japanese Foundation for Cancer Research, Tokyo, JapanDepartment of Orthopedic Oncology, Cancer Institute Hospital of the Japanese Foundation for Cancer Research, Tokyo, JapanDepartment of Orthopedic Oncology, Cancer Institute Hospital of the Japanese Foundation for Cancer Research, Tokyo, JapanDepartment of Orthopedic Oncology, Cancer Institute Hospital of the Japanese Foundation for Cancer Research, Tokyo, JapanDepartment of Orthopedic Oncology, Cancer Institute Hospital of the Japanese Foundation for Cancer Research, Tokyo, JapanCombined limb salvage surgery and radiation therapy has been gaining traction for the treatment of soft tissue sarcomas of the foot in recent years. However, limb salvage surgery without radiation therapy is more desirable. In this study, we obtained good results from limb salvage surgery without radiation therapy in soft tissue sarcoma of the foot. Twenty patients histologically diagnosed with soft tissue sarcoma who underwent limb salvage surgery, including ray amputation, were evaluated. Their mean age was 39 years. The mean follow-up period was 94.5 months (6–355 months). The histological diagnoses included 9 cases of synovial sarcoma. Treatment, local recurrence rate, survival rate, complication, and ADL were evaluated. Surgical procedures consisted of ray amputation in 5 cases and limb salvage surgery in 15. Of these 15 cases, 14 (93%) required reconstructive surgery for skin defects. One patient (5%) exhibited recurrence. The 5-year overall survival rate was 94.7%, and the 5-year local progression-free survival rate was 92.9%. Early postoperative complications were found in 5 of 20 cases (25%), comprising flap failure in 4 cases and infection in 1 case; however, all patients eventually demonstrated good functional outcomes. In this study, the recurrence rate was 5% for patients who underwent limb salvage surgery without radiation therapy, and we obtained good local control. Since the anatomical structures of the foot act as barriers to tumor progression, the use of a method of evaluating resection margins to determine the extent of resection enabled successful surgery, not combined with radiation, without the recurrence of sarcomas.http://www.sciencedirect.com/science/article/pii/S2667396721000975Foot lesionMalignant soft tissue tumorOperationTreatmentUnplanned excision |
| spellingShingle | Keiko Hayakawa Seiichi Matsumoto Keisuke Ae Taisuke Tanizawa Yuki Funauchi Yusuke Minami Masanori Saito Limb salvage surgery without radiation therapy for soft tissue sarcomas of the foot Foot & Ankle Surgery: Techniques, Reports & Cases Foot lesion Malignant soft tissue tumor Operation Treatment Unplanned excision |
| title | Limb salvage surgery without radiation therapy for soft tissue sarcomas of the foot |
| title_full | Limb salvage surgery without radiation therapy for soft tissue sarcomas of the foot |
| title_fullStr | Limb salvage surgery without radiation therapy for soft tissue sarcomas of the foot |
| title_full_unstemmed | Limb salvage surgery without radiation therapy for soft tissue sarcomas of the foot |
| title_short | Limb salvage surgery without radiation therapy for soft tissue sarcomas of the foot |
| title_sort | limb salvage surgery without radiation therapy for soft tissue sarcomas of the foot |
| topic | Foot lesion Malignant soft tissue tumor Operation Treatment Unplanned excision |
| url | http://www.sciencedirect.com/science/article/pii/S2667396721000975 |
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