Research progress of Posner-Schlossman syndrome
Posner-Schlossman syndrome(PSS)is a sporadic and recurrent self-limiting anterior uveitis, and its pathogenesis remains unclear. It was considered to be a prostaglandin-mediated inflammatory response. In recent years, it has been found to be related to viral infection, immune genetics, vascular endo...
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2023-10-01
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| Series: | Guoji Yanke Zazhi |
| Subjects: | |
| Online Access: | http://ies.ijo.cn/cn_publish/2023/10/202310014.pdf |
| _version_ | 1797682026087710720 |
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| author | Xin-Hao Gong Yu-Fang Teng |
| author_facet | Xin-Hao Gong Yu-Fang Teng |
| author_sort | Xin-Hao Gong |
| collection | DOAJ |
| description | Posner-Schlossman syndrome(PSS)is a sporadic and recurrent self-limiting anterior uveitis, and its pathogenesis remains unclear. It was considered to be a prostaglandin-mediated inflammatory response. In recent years, it has been found to be related to viral infection, immune genetics, vascular endothelial dysfunction, and other factors. Clinically, the disease is predominantly unilateral. The patients with PSS suffer from increased intraocular pressure, mild pain in the affected eye, as well as blurred vision, and irisopsia. Seldom damage to the optic nerve and visual field was reported. The commonly treatment of PSS is local medication, such as anti-inflammatory drugs and intraocular pressure lowering drugs; otherwise systemic medication can be employed in severe cases. Surgical treatment can be performed for PSS if uncontrolled intraocular pressure elevation, frequent attacks, and optic nerve damage and visual field defect due to prolonged disease course. Early diagnosis and treatment of PSS can effectively reduce glaucoma-related damages. This review discussed the research progress of PSS from various aspects, aiming to provide references for the etiology, pathogenesis, and clinical diagnosis and treatment of this disease. |
| first_indexed | 2024-03-11T23:53:33Z |
| format | Article |
| id | doaj.art-d75ddc06688f45418d03ef0942815079 |
| institution | Directory Open Access Journal |
| issn | 1672-5123 |
| language | English |
| last_indexed | 2024-03-11T23:53:33Z |
| publishDate | 2023-10-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | Guoji Yanke Zazhi |
| spelling | doaj.art-d75ddc06688f45418d03ef09428150792023-09-19T03:02:27ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51232023-10-0123101671167610.3980/j.issn.1672-5123.2023.10.14202310014Research progress of Posner-Schlossman syndromeXin-Hao Gong0Yu-Fang Teng1Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan 250117, Shandong Province, ChinaDepartment of Ophthalmology, the Second Affiliated Hospital of Shandong First Medical University, Taian 271000, Shandong Province, ChinaPosner-Schlossman syndrome(PSS)is a sporadic and recurrent self-limiting anterior uveitis, and its pathogenesis remains unclear. It was considered to be a prostaglandin-mediated inflammatory response. In recent years, it has been found to be related to viral infection, immune genetics, vascular endothelial dysfunction, and other factors. Clinically, the disease is predominantly unilateral. The patients with PSS suffer from increased intraocular pressure, mild pain in the affected eye, as well as blurred vision, and irisopsia. Seldom damage to the optic nerve and visual field was reported. The commonly treatment of PSS is local medication, such as anti-inflammatory drugs and intraocular pressure lowering drugs; otherwise systemic medication can be employed in severe cases. Surgical treatment can be performed for PSS if uncontrolled intraocular pressure elevation, frequent attacks, and optic nerve damage and visual field defect due to prolonged disease course. Early diagnosis and treatment of PSS can effectively reduce glaucoma-related damages. This review discussed the research progress of PSS from various aspects, aiming to provide references for the etiology, pathogenesis, and clinical diagnosis and treatment of this disease.http://ies.ijo.cn/cn_publish/2023/10/202310014.pdfposner-schlossman syndromeglaucomatocyclitic crisissecondary glaucomaanterior uveitiscytomegalovirusglaucomatous optic nerve damage |
| spellingShingle | Xin-Hao Gong Yu-Fang Teng Research progress of Posner-Schlossman syndrome Guoji Yanke Zazhi posner-schlossman syndrome glaucomatocyclitic crisis secondary glaucoma anterior uveitis cytomegalovirus glaucomatous optic nerve damage |
| title | Research progress of Posner-Schlossman syndrome |
| title_full | Research progress of Posner-Schlossman syndrome |
| title_fullStr | Research progress of Posner-Schlossman syndrome |
| title_full_unstemmed | Research progress of Posner-Schlossman syndrome |
| title_short | Research progress of Posner-Schlossman syndrome |
| title_sort | research progress of posner schlossman syndrome |
| topic | posner-schlossman syndrome glaucomatocyclitic crisis secondary glaucoma anterior uveitis cytomegalovirus glaucomatous optic nerve damage |
| url | http://ies.ijo.cn/cn_publish/2023/10/202310014.pdf |
| work_keys_str_mv | AT xinhaogong researchprogressofposnerschlossmansyndrome AT yufangteng researchprogressofposnerschlossmansyndrome |