Mutation Status and Glucose Availability Affect the Response to Mitochondria-Targeted Quercetin Derivative in Breast Cancer Cells

Mutation Status and Glucose Availability Affect the Response to Mitochondria-Targeted Quercetin Derivative in Breast Cancer Cells

Mitochondria, the main cellular power stations, are important modulators of redox-sensitive signaling pathways that may determine cell survival and cell death decisions. As mitochondrial function is essential for tumorigenesis and cancer progression, mitochondrial targeting has been proposed as an a...

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Bibliographic Details
Main Authors: Paweł Przybylski, Anna Lewińska, Iwona Rzeszutek, Dominika Błoniarz, Aleksandra Moskal, Gabriela Betlej, Anna Deręgowska, Martyna Cybularczyk-Cecotka, Tomasz Szmatoła, Grzegorz Litwinienko, Maciej Wnuk
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Cancers
Subjects:
mito-quercetin
breast cancer
oxidative stress
AMPK
doxorubicin-induced senescence
senolysis
Online Access:https://www.mdpi.com/2072-6694/15/23/5614

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