Synthesis of Prussian Blue Nanoparticles and Their Antibacterial, Antiinflammation and Antitumor Applications
In recent years, Prussian blue nanoparticles (PBNPs), also named Prussian blue nano-enzymes, have been shown to demonstrate excellent multi-enzyme simulation activity and anti-inflammatory properties, and can be used as reactive oxygen scavengers. Their good biocompatibility and biodegradability mea...
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| Format: | Article |
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MDPI AG
2022-06-01
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| Series: | Pharmaceuticals |
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| Online Access: | https://www.mdpi.com/1424-8247/15/7/769 |
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| author | Danyang Li Meng Liu Wenyao Li Qiang Fu Liyang Wang Enping Lai Weixin Zhao Kaile Zhang |
| author_facet | Danyang Li Meng Liu Wenyao Li Qiang Fu Liyang Wang Enping Lai Weixin Zhao Kaile Zhang |
| author_sort | Danyang Li |
| collection | DOAJ |
| description | In recent years, Prussian blue nanoparticles (PBNPs), also named Prussian blue nano-enzymes, have been shown to demonstrate excellent multi-enzyme simulation activity and anti-inflammatory properties, and can be used as reactive oxygen scavengers. Their good biocompatibility and biodegradability mean that they are ideal candidates for in vivo use. PBNPs are highly efficient electron transporters with oxidation and reduction activities. PBNPs also show considerable promise as nano-drug carriers and biological detection sensors owing to their huge specific surface area, good chemical characteristics, and changeable qualities, which might considerably increase the therapeutic impact. More crucially, PBNPs, as therapeutic and diagnostic agents, have made significant advances in biological nanomedicine. This review begins with a brief description of the synthesis methods of PBNPs, then focuses on the applications of PBNPs in tissue regeneration and inflammation according to the different properties of PBNPs. This article will provide a timely reference for further study of PBNPs as therapeutic agents. |
| first_indexed | 2024-03-09T13:12:58Z |
| format | Article |
| id | doaj.art-d7608c7d2f434a03ab667d3fc4228a6b |
| institution | Directory Open Access Journal |
| issn | 1424-8247 |
| language | English |
| last_indexed | 2024-03-09T13:12:58Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceuticals |
| spelling | doaj.art-d7608c7d2f434a03ab667d3fc4228a6b2023-11-30T21:39:54ZengMDPI AGPharmaceuticals1424-82472022-06-0115776910.3390/ph15070769Synthesis of Prussian Blue Nanoparticles and Their Antibacterial, Antiinflammation and Antitumor ApplicationsDanyang Li0Meng Liu1Wenyao Li2Qiang Fu3Liyang Wang4Enping Lai5Weixin Zhao6Kaile Zhang7The Department of Urology, Affiliated Sixth People’s Hospital, Shanghai Jiao Tong University, Shanghai 200233, ChinaThe Department of Urology, Affiliated Sixth People’s Hospital, Shanghai Jiao Tong University, Shanghai 200233, ChinaSchool of Materials Engineering, Shanghai University of Engineering Science, Shanghai 201620, ChinaThe Department of Urology, Affiliated Sixth People’s Hospital, Shanghai Jiao Tong University, Shanghai 200233, ChinaSchool of Materials Engineering, Shanghai University of Engineering Science, Shanghai 201620, ChinaGuangxi Key Laboratory of Green Processing of Sugar Resources, College of Biological and Chemical Engineering, Guangxi University of Science and Technology, Liuzhou 545026, ChinaWake Forest Institute of Regenerative Medicine, Winston Salem, NC 27101, USAThe Department of Urology, Affiliated Sixth People’s Hospital, Shanghai Jiao Tong University, Shanghai 200233, ChinaIn recent years, Prussian blue nanoparticles (PBNPs), also named Prussian blue nano-enzymes, have been shown to demonstrate excellent multi-enzyme simulation activity and anti-inflammatory properties, and can be used as reactive oxygen scavengers. Their good biocompatibility and biodegradability mean that they are ideal candidates for in vivo use. PBNPs are highly efficient electron transporters with oxidation and reduction activities. PBNPs also show considerable promise as nano-drug carriers and biological detection sensors owing to their huge specific surface area, good chemical characteristics, and changeable qualities, which might considerably increase the therapeutic impact. More crucially, PBNPs, as therapeutic and diagnostic agents, have made significant advances in biological nanomedicine. This review begins with a brief description of the synthesis methods of PBNPs, then focuses on the applications of PBNPs in tissue regeneration and inflammation according to the different properties of PBNPs. This article will provide a timely reference for further study of PBNPs as therapeutic agents.https://www.mdpi.com/1424-8247/15/7/769Prussian blue nanoparticlestissue repairanti-inflammatory effectsnano-enzymedrug carrier |
| spellingShingle | Danyang Li Meng Liu Wenyao Li Qiang Fu Liyang Wang Enping Lai Weixin Zhao Kaile Zhang Synthesis of Prussian Blue Nanoparticles and Their Antibacterial, Antiinflammation and Antitumor Applications Pharmaceuticals Prussian blue nanoparticles tissue repair anti-inflammatory effects nano-enzyme drug carrier |
| title | Synthesis of Prussian Blue Nanoparticles and Their Antibacterial, Antiinflammation and Antitumor Applications |
| title_full | Synthesis of Prussian Blue Nanoparticles and Their Antibacterial, Antiinflammation and Antitumor Applications |
| title_fullStr | Synthesis of Prussian Blue Nanoparticles and Their Antibacterial, Antiinflammation and Antitumor Applications |
| title_full_unstemmed | Synthesis of Prussian Blue Nanoparticles and Their Antibacterial, Antiinflammation and Antitumor Applications |
| title_short | Synthesis of Prussian Blue Nanoparticles and Their Antibacterial, Antiinflammation and Antitumor Applications |
| title_sort | synthesis of prussian blue nanoparticles and their antibacterial antiinflammation and antitumor applications |
| topic | Prussian blue nanoparticles tissue repair anti-inflammatory effects nano-enzyme drug carrier |
| url | https://www.mdpi.com/1424-8247/15/7/769 |
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