Shedding new light on circadian clocks
Using a clever combination of genetic and biochemical tools researchers have shown that a transcription factor called USF1 has a central role in determining how mutations of the Clock gene manifest themselves in the behaviour of different mouse strains.
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
eLife Sciences Publications Ltd
2013-04-01
|
| Series: | eLife |
| Subjects: | |
| Online Access: | https://elifesciences.org/articles/00659 |
| _version_ | 1811253400349704192 |
|---|---|
| author | Maud Demarque Ueli Schibler |
| author_facet | Maud Demarque Ueli Schibler |
| author_sort | Maud Demarque |
| collection | DOAJ |
| description | Using a clever combination of genetic and biochemical tools researchers have shown that a transcription factor called USF1 has a central role in determining how mutations of the Clock gene manifest themselves in the behaviour of different mouse strains. |
| first_indexed | 2024-04-12T16:50:21Z |
| format | Article |
| id | doaj.art-d762a89dbfc2400fad4ca5686fb1042f |
| institution | Directory Open Access Journal |
| issn | 2050-084X |
| language | English |
| last_indexed | 2024-04-12T16:50:21Z |
| publishDate | 2013-04-01 |
| publisher | eLife Sciences Publications Ltd |
| record_format | Article |
| series | eLife |
| spelling | doaj.art-d762a89dbfc2400fad4ca5686fb1042f2022-12-22T03:24:25ZengeLife Sciences Publications LtdeLife2050-084X2013-04-01210.7554/eLife.00659Shedding new light on circadian clocksMaud Demarque0Ueli Schibler1Department of Molecular Biology, University of Geneva, Geneva, Switzerlandthe Department of Molecular Biology, University of Geneva, Geneva, SwitzerlandUsing a clever combination of genetic and biochemical tools researchers have shown that a transcription factor called USF1 has a central role in determining how mutations of the Clock gene manifest themselves in the behaviour of different mouse strains.https://elifesciences.org/articles/00659Clock geneUSF1genetic modifiercircadian rhythmmouse geneticChIP-Seq |
| spellingShingle | Maud Demarque Ueli Schibler Shedding new light on circadian clocks eLife Clock gene USF1 genetic modifier circadian rhythm mouse genetic ChIP-Seq |
| title | Shedding new light on circadian clocks |
| title_full | Shedding new light on circadian clocks |
| title_fullStr | Shedding new light on circadian clocks |
| title_full_unstemmed | Shedding new light on circadian clocks |
| title_short | Shedding new light on circadian clocks |
| title_sort | shedding new light on circadian clocks |
| topic | Clock gene USF1 genetic modifier circadian rhythm mouse genetic ChIP-Seq |
| url | https://elifesciences.org/articles/00659 |
| work_keys_str_mv | AT mauddemarque sheddingnewlightoncircadianclocks AT uelischibler sheddingnewlightoncircadianclocks |