Long-term effects from bacterial meningitis in childhood and adolescence on postural control.
Bacterial meningitis in childhood is associated with cognitive deficiencies, sensorimotor impairments and motor dysfunction later in life. However, the long-term effects on postural control is largely unknown, e.g., whether meningitis subjects as adults fully can utilize visual information and adapt...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4236047?pdf=render |
| _version_ | 1811210832986505216 |
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| author | Hannes Petersen Mitesh Patel Mitesh Patel Einar F Ingason Einar J Einarsson Ásgeir Haraldsson Per-Anders Fransson |
| author_facet | Hannes Petersen Mitesh Patel Mitesh Patel Einar F Ingason Einar J Einarsson Ásgeir Haraldsson Per-Anders Fransson |
| author_sort | Hannes Petersen |
| collection | DOAJ |
| description | Bacterial meningitis in childhood is associated with cognitive deficiencies, sensorimotor impairments and motor dysfunction later in life. However, the long-term effects on postural control is largely unknown, e.g., whether meningitis subjects as adults fully can utilize visual information and adaptation to enhance stability. Thirty-six subjects (20 women, mean age 19.3 years) treated in childhood or adolescence for bacterial meningitis, and 25 controls (13 women, mean age 25.1 years) performed posturography with eyes open and closed under unperturbed and perturbed standing. The meningitis subjects were screened for subjective vertigo symptoms using a questionnaire, clinically tested with headshake and head thrust test, as well as their hearing was evaluated. Meningitis subjects were significantly more unstable than controls during unperturbed (p≤0.014) and perturbed standing, though while perturbed only with eyes open in anteroposterior direction (p = 0.034) whereas in lateral direction both with eyes open and closed (p<0.001). Meningitis subjects had poorer adaption ability to balance perturbations especially with eyes open, and they frequently reported symptoms of unsteadiness (88% of the subjects) and dizziness (81%), which was found significantly correlated to objectively decreased stability. Out of the 36 subjects only 3 had unilateral hearing impairment. Hence, survivors of childhood bacterial meningitis may suffer long-term disorders affecting postural control, and would greatly benefit if these common late effects became generally known so treatments can be developed and applied. |
| first_indexed | 2024-04-12T05:01:47Z |
| format | Article |
| id | doaj.art-d76597458d2143ee96136f0886fa5131 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-12T05:01:47Z |
| publishDate | 2014-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-d76597458d2143ee96136f0886fa51312022-12-22T03:46:58ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-01911e11201610.1371/journal.pone.0112016Long-term effects from bacterial meningitis in childhood and adolescence on postural control.Hannes PetersenMitesh PatelMitesh PatelEinar F IngasonEinar J EinarssonÁsgeir HaraldssonPer-Anders FranssonBacterial meningitis in childhood is associated with cognitive deficiencies, sensorimotor impairments and motor dysfunction later in life. However, the long-term effects on postural control is largely unknown, e.g., whether meningitis subjects as adults fully can utilize visual information and adaptation to enhance stability. Thirty-six subjects (20 women, mean age 19.3 years) treated in childhood or adolescence for bacterial meningitis, and 25 controls (13 women, mean age 25.1 years) performed posturography with eyes open and closed under unperturbed and perturbed standing. The meningitis subjects were screened for subjective vertigo symptoms using a questionnaire, clinically tested with headshake and head thrust test, as well as their hearing was evaluated. Meningitis subjects were significantly more unstable than controls during unperturbed (p≤0.014) and perturbed standing, though while perturbed only with eyes open in anteroposterior direction (p = 0.034) whereas in lateral direction both with eyes open and closed (p<0.001). Meningitis subjects had poorer adaption ability to balance perturbations especially with eyes open, and they frequently reported symptoms of unsteadiness (88% of the subjects) and dizziness (81%), which was found significantly correlated to objectively decreased stability. Out of the 36 subjects only 3 had unilateral hearing impairment. Hence, survivors of childhood bacterial meningitis may suffer long-term disorders affecting postural control, and would greatly benefit if these common late effects became generally known so treatments can be developed and applied.http://europepmc.org/articles/PMC4236047?pdf=render |
| spellingShingle | Hannes Petersen Mitesh Patel Mitesh Patel Einar F Ingason Einar J Einarsson Ásgeir Haraldsson Per-Anders Fransson Long-term effects from bacterial meningitis in childhood and adolescence on postural control. PLoS ONE |
| title | Long-term effects from bacterial meningitis in childhood and adolescence on postural control. |
| title_full | Long-term effects from bacterial meningitis in childhood and adolescence on postural control. |
| title_fullStr | Long-term effects from bacterial meningitis in childhood and adolescence on postural control. |
| title_full_unstemmed | Long-term effects from bacterial meningitis in childhood and adolescence on postural control. |
| title_short | Long-term effects from bacterial meningitis in childhood and adolescence on postural control. |
| title_sort | long term effects from bacterial meningitis in childhood and adolescence on postural control |
| url | http://europepmc.org/articles/PMC4236047?pdf=render |
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