Exploration and validation of key genes associated with early lymph node metastasis in thyroid carcinoma using weighted gene co-expression network analysis and machine learning

Exploration and validation of key genes associated with early lymph node metastasis in thyroid carcinoma using weighted gene co-expression network analysis and machine learning

BackgroundThyroid carcinoma (THCA), the most common endocrine neoplasm, typically exhibits an indolent behavior. However, in some instances, lymph node metastasis (LNM) may occur in the early stages, with the underlying mechanisms not yet fully understood.Materials and methodsLNM potential was defin...

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Bibliographic Details
Main Authors: Yanyan Liu, Zhenglang Yin, Yao Wang, Haohao Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Endocrinology
Subjects:
thyroid cancer
bioinformatics analysis
The Cancer Genome Atlas
nomogram
machine learning
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1247709/full

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