Precision Medicine and Pediatric Epilepsy

Recently, it is time to shift from a reactive attitude that treats patients after the onset of seizures to a proactive one integrated into a broader “P4 medicine” approach in the treatment of epilepsy. Personalized, predictive, preventive, and participatory, this P4 approach puts patients at the cen...

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Main Authors: Aycan Ünalp, Erdem Adalıoğlu
Format: Article
Language:English
Published: Galenos Yayinevi 2022-06-01
Series:Archives of Epilepsy
Subjects:
Online Access: http://archepilepsy.org/archives/archive-detail/article-preview/precision-medicine-and-pediatric-epilepsy/54586
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author Aycan Ünalp
Erdem Adalıoğlu
author_facet Aycan Ünalp
Erdem Adalıoğlu
author_sort Aycan Ünalp
collection DOAJ
description Recently, it is time to shift from a reactive attitude that treats patients after the onset of seizures to a proactive one integrated into a broader “P4 medicine” approach in the treatment of epilepsy. Personalized, predictive, preventive, and participatory, this P4 approach puts patients at the center of their care and ultimately aims to prevent the onset of epilepsy. This goal will be achieved by tailoring epilepsy treatments not only to a particular syndrome but also to a particular patient and moving from the usual anti-seizure treatments to individualized treatments designed to target specific etiologies. In this review, we present the current state of this ongoing revolution, highlighting the emergence of the concepts of precision medicine and individualized medicine and its impact on clinical practice in pediatric epilepsies.
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spelling doaj.art-d76a66a990c24fdf968067e23cbff45e2023-08-01T11:12:29ZengGalenos YayineviArchives of Epilepsy2792-05502022-06-01282485210.54614/ArchEpilepsy.2022.0565713049054Precision Medicine and Pediatric EpilepsyAycan Ünalp0Erdem Adalıoğlu1 Department of Pediatrics, Division of Pediatric Neurology, Health Sciences University, Faculty of Medicine, İzmir, Turkey Department of Pediatry, Special Hospital of İzmir Ege City, İzmir, Turkey Recently, it is time to shift from a reactive attitude that treats patients after the onset of seizures to a proactive one integrated into a broader “P4 medicine” approach in the treatment of epilepsy. Personalized, predictive, preventive, and participatory, this P4 approach puts patients at the center of their care and ultimately aims to prevent the onset of epilepsy. This goal will be achieved by tailoring epilepsy treatments not only to a particular syndrome but also to a particular patient and moving from the usual anti-seizure treatments to individualized treatments designed to target specific etiologies. In this review, we present the current state of this ongoing revolution, highlighting the emergence of the concepts of precision medicine and individualized medicine and its impact on clinical practice in pediatric epilepsies. http://archepilepsy.org/archives/archive-detail/article-preview/precision-medicine-and-pediatric-epilepsy/54586 pediatric epilepsyprecisionpersonalizedpreventivemedicine
spellingShingle Aycan Ünalp
Erdem Adalıoğlu
Precision Medicine and Pediatric Epilepsy
Archives of Epilepsy
pediatric epilepsy
precision
personalized
preventive
medicine
title Precision Medicine and Pediatric Epilepsy
title_full Precision Medicine and Pediatric Epilepsy
title_fullStr Precision Medicine and Pediatric Epilepsy
title_full_unstemmed Precision Medicine and Pediatric Epilepsy
title_short Precision Medicine and Pediatric Epilepsy
title_sort precision medicine and pediatric epilepsy
topic pediatric epilepsy
precision
personalized
preventive
medicine
url http://archepilepsy.org/archives/archive-detail/article-preview/precision-medicine-and-pediatric-epilepsy/54586
work_keys_str_mv AT aycanunalp precisionmedicineandpediatricepilepsy
AT erdemadalıoglu precisionmedicineandpediatricepilepsy