Extraction and measurement of urinary tetranor-PGDM in disposable diapers

Urinary tetranor-PGDM is a useful diagnostic biomarker for food allergy which often affects infants. We attempted to extract and measure urinary tetranor-PGDM absorbed in polymer of diapers. We applied CaCl2 to the collected polymer, determined the adequate time length of shaking the polymer to rele...

Ամբողջական նկարագրություն

Մատենագիտական մանրամասներ
Հիմնական հեղինակներ: Nagisa Ito, Tatsuro Nakamura, Naoaki Sakamoto, Akane Hayashi, Takahisa Murata
Ձևաչափ: Հոդված
Լեզու:English
Հրապարակվել է: Elsevier 2021-10-01
Շարք:Journal of Pharmacological Sciences
Խորագրեր:
Առցանց հասանելիություն:http://www.sciencedirect.com/science/article/pii/S1347861321000670
Նկարագրություն
Ամփոփում:Urinary tetranor-PGDM is a useful diagnostic biomarker for food allergy which often affects infants. We attempted to extract and measure urinary tetranor-PGDM absorbed in polymer of diapers. We applied CaCl2 to the collected polymer, determined the adequate time length of shaking the polymer to release urine, and measured tetranor-PGDM in the extracted urine. This procedure provided high linearity and recovery rate in tetranor-PGDM measurement. We also found that urinary tetranor-PGDM was stable for 24 h at 4°C in diapers. This method can be useful to monitor the food allergic condition of non-toilet trained children.
ISSN:1347-8613