Cocaine and Volatile Nitrite–Induced Methemoglobinemia; a Case Report and Treatment Approach Review

Cyanosis is typically a sign of a potentially life-threatening condition in the emergency department and requires immediate workup and treatment. This case report highlights the diagnostic reasoning and clinical approach to cocaine- and volatile nitrite–induced methemoglobinemia (MHG). MHG is a rar...

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Main Authors: Milena Ribeiro Paixão, Tarso Augusto Duenhas Accorsi, Luis Felipe Lopes Prada, Lucas Zoboli Pocebon, Karine De Amicis Lima, Karen Francine Köhler, Leandro Santini Echenique, José Leão de Souza Júnior
Format: Article
Language:English
Published: Shahid Beheshti University of Medical Sciences 2022-09-01
Series:Archives of Academic Emergency Medicine
Subjects:
Online Access:https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/1753
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author Milena Ribeiro Paixão
Tarso Augusto Duenhas Accorsi
Luis Felipe Lopes Prada
Lucas Zoboli Pocebon
Karine De Amicis Lima
Karen Francine Köhler
Leandro Santini Echenique
José Leão de Souza Júnior
author_facet Milena Ribeiro Paixão
Tarso Augusto Duenhas Accorsi
Luis Felipe Lopes Prada
Lucas Zoboli Pocebon
Karine De Amicis Lima
Karen Francine Köhler
Leandro Santini Echenique
José Leão de Souza Júnior
author_sort Milena Ribeiro Paixão
collection DOAJ
description Cyanosis is typically a sign of a potentially life-threatening condition in the emergency department and requires immediate workup and treatment. This case report highlights the diagnostic reasoning and clinical approach to cocaine- and volatile nitrite–induced methemoglobinemia (MHG). MHG is a rare, life-threatening cause of cyanosis. The diagnosis must be suspected in the emergency department in the presence of hypoxia and cyanosis disproportionate to cardiopulmonary repercussions and refractory to oxygen supplementation. Acquired causes are more prevalent than genetics, and recreational drugs should be highly suspected. Despite the rarity of this situation, cyanosis precipitants and the specificities of each hemoglobinopathy are reviewed in this article.
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spelling doaj.art-d76c90ec2fd84d57b08e87f8cc8c7f812022-12-22T04:05:36ZengShahid Beheshti University of Medical SciencesArchives of Academic Emergency Medicine2645-49042022-09-0110110.22037/aaem.v10i1.1753Cocaine and Volatile Nitrite–Induced Methemoglobinemia; a Case Report and Treatment Approach ReviewMilena Ribeiro Paixão0Tarso Augusto Duenhas AccorsiLuis Felipe Lopes PradaLucas Zoboli PocebonKarine De Amicis LimaKaren Francine KöhlerLeandro Santini EcheniqueJosé Leão de Souza JúniorEmergency Department, Hospital Israelita Albert Einstein, Sao Paulo, Brazil Cyanosis is typically a sign of a potentially life-threatening condition in the emergency department and requires immediate workup and treatment. This case report highlights the diagnostic reasoning and clinical approach to cocaine- and volatile nitrite–induced methemoglobinemia (MHG). MHG is a rare, life-threatening cause of cyanosis. The diagnosis must be suspected in the emergency department in the presence of hypoxia and cyanosis disproportionate to cardiopulmonary repercussions and refractory to oxygen supplementation. Acquired causes are more prevalent than genetics, and recreational drugs should be highly suspected. Despite the rarity of this situation, cyanosis precipitants and the specificities of each hemoglobinopathy are reviewed in this article. https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/1753MethemoglobinemiaCocaineNitritesEmergency MedicineCase Report
spellingShingle Milena Ribeiro Paixão
Tarso Augusto Duenhas Accorsi
Luis Felipe Lopes Prada
Lucas Zoboli Pocebon
Karine De Amicis Lima
Karen Francine Köhler
Leandro Santini Echenique
José Leão de Souza Júnior
Cocaine and Volatile Nitrite–Induced Methemoglobinemia; a Case Report and Treatment Approach Review
Archives of Academic Emergency Medicine
Methemoglobinemia
Cocaine
Nitrites
Emergency Medicine
Case Report
title Cocaine and Volatile Nitrite–Induced Methemoglobinemia; a Case Report and Treatment Approach Review
title_full Cocaine and Volatile Nitrite–Induced Methemoglobinemia; a Case Report and Treatment Approach Review
title_fullStr Cocaine and Volatile Nitrite–Induced Methemoglobinemia; a Case Report and Treatment Approach Review
title_full_unstemmed Cocaine and Volatile Nitrite–Induced Methemoglobinemia; a Case Report and Treatment Approach Review
title_short Cocaine and Volatile Nitrite–Induced Methemoglobinemia; a Case Report and Treatment Approach Review
title_sort cocaine and volatile nitrite induced methemoglobinemia a case report and treatment approach review
topic Methemoglobinemia
Cocaine
Nitrites
Emergency Medicine
Case Report
url https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/1753
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