Clinico-pathological correlates of incidentally revealed thyroid swelling in Bihar, India

Background: Global prevalence of thyroid cancer has been on the rise in recent decades. Objectives: To study the clinical presentations to reach an agreement for diagnosis and optimal management of incidentally revealed thyroid swellings for early diagnosis. Materials and Methods: A prospective stud...

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Main Authors: Arup Sengupta, Ranabir Pal, Sumit Kar, Forhad Akhtar Zaman, Mausumi Basu, Shrayan Pal
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2012-01-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
Online Access:http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2012;volume=4;issue=1;spage=51;epage=55;aulast=Sengupta
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author Arup Sengupta
Ranabir Pal
Sumit Kar
Forhad Akhtar Zaman
Mausumi Basu
Shrayan Pal
author_facet Arup Sengupta
Ranabir Pal
Sumit Kar
Forhad Akhtar Zaman
Mausumi Basu
Shrayan Pal
author_sort Arup Sengupta
collection DOAJ
description Background: Global prevalence of thyroid cancer has been on the rise in recent decades. Objectives: To study the clinical presentations to reach an agreement for diagnosis and optimal management of incidentally revealed thyroid swellings for early diagnosis. Materials and Methods: A prospective study was carried out on 178 cases of incidentally detected thyroid swelling attending a tertiary care teaching institute of Kishanganj Bihar. All the cases were subjected to a thorough clinical examination followed by evidence-based interventions. Fine needle aspiration cytology was done in all the cases preoperatively as out-patients basis and histopathologically confirmed postoperatively. Results: The highest incidence of thyroid swelling (75.84%) was found in the age group of 20-40 years; a female preponderance was noted in the ratio 4:1. The duration of swelling ranged from six months to three years. Difficulty in swallowing and breathing was complained by 23 (12.9%) and 18 (10.1%) of the patients respectively. Typically the swellings were located in the right lobe. Commonly the subjects in our study were in euthyroid state (90%) and were with firm swellings (66.7%). Follicular and anaplastic carcinoma was important postoperative cytological findings. Majority of surgical intervention was hemithyroidectomy (55.06%). Conclusion: Incidentally revealed thyroid swelling was quite high in eastern India for which we need a consensus line of intervention.
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spelling doaj.art-d76d0db046df46a9b9991667f51845432022-12-21T19:10:37ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0975-74060976-48792012-01-0141515510.4103/0975-7406.92730Clinico-pathological correlates of incidentally revealed thyroid swelling in Bihar, IndiaArup SenguptaRanabir PalSumit KarForhad Akhtar ZamanMausumi BasuShrayan PalBackground: Global prevalence of thyroid cancer has been on the rise in recent decades. Objectives: To study the clinical presentations to reach an agreement for diagnosis and optimal management of incidentally revealed thyroid swellings for early diagnosis. Materials and Methods: A prospective study was carried out on 178 cases of incidentally detected thyroid swelling attending a tertiary care teaching institute of Kishanganj Bihar. All the cases were subjected to a thorough clinical examination followed by evidence-based interventions. Fine needle aspiration cytology was done in all the cases preoperatively as out-patients basis and histopathologically confirmed postoperatively. Results: The highest incidence of thyroid swelling (75.84%) was found in the age group of 20-40 years; a female preponderance was noted in the ratio 4:1. The duration of swelling ranged from six months to three years. Difficulty in swallowing and breathing was complained by 23 (12.9%) and 18 (10.1%) of the patients respectively. Typically the swellings were located in the right lobe. Commonly the subjects in our study were in euthyroid state (90%) and were with firm swellings (66.7%). Follicular and anaplastic carcinoma was important postoperative cytological findings. Majority of surgical intervention was hemithyroidectomy (55.06%). Conclusion: Incidentally revealed thyroid swelling was quite high in eastern India for which we need a consensus line of intervention.http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2012;volume=4;issue=1;spage=51;epage=55;aulast=SenguptaBiharthyroid swellingfine needle aspiration cytology
spellingShingle Arup Sengupta
Ranabir Pal
Sumit Kar
Forhad Akhtar Zaman
Mausumi Basu
Shrayan Pal
Clinico-pathological correlates of incidentally revealed thyroid swelling in Bihar, India
Journal of Pharmacy and Bioallied Sciences
Bihar
thyroid swelling
fine needle aspiration cytology
title Clinico-pathological correlates of incidentally revealed thyroid swelling in Bihar, India
title_full Clinico-pathological correlates of incidentally revealed thyroid swelling in Bihar, India
title_fullStr Clinico-pathological correlates of incidentally revealed thyroid swelling in Bihar, India
title_full_unstemmed Clinico-pathological correlates of incidentally revealed thyroid swelling in Bihar, India
title_short Clinico-pathological correlates of incidentally revealed thyroid swelling in Bihar, India
title_sort clinico pathological correlates of incidentally revealed thyroid swelling in bihar india
topic Bihar
thyroid swelling
fine needle aspiration cytology
url http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2012;volume=4;issue=1;spage=51;epage=55;aulast=Sengupta
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