A case of MDS/MPN overlap syndrome with ring sideroblasts and thrombocytosis: Tackling the quandary of thrombosis versus hemorrhage
Key Clinical Message No formal treatment guidelines for MDS/MPN‐RS‐T exist. With salient features such as anemia and thrombocytosis, management is individualized and aims to address anemia, thrombosis, and in some cases acquired von Willebrand's disease. Abstract Myelodysplastic/myeloproliferat...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-06-01
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| Series: | Clinical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ccr3.7409 |
| _version_ | 1797791770075987968 |
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| author | Hannah Cherniawsky Habib Moshref Razavi |
| author_facet | Hannah Cherniawsky Habib Moshref Razavi |
| author_sort | Hannah Cherniawsky |
| collection | DOAJ |
| description | Key Clinical Message No formal treatment guidelines for MDS/MPN‐RS‐T exist. With salient features such as anemia and thrombocytosis, management is individualized and aims to address anemia, thrombosis, and in some cases acquired von Willebrand's disease. Abstract Myelodysplastic/myeloproliferative overlap syndrome with ring sideroblasts and thrombocytosis (MDS/MPN‐RS‐T) is a rare myeloid neoplasm showing myelodysplastic and myeloproliferative features. With extremely raised platelets, possibility of acquired von Willebrand and risk of hemorrhage is increased. With this quandary in mind, a descriptive case and a brief discussion of available treatments ensues. |
| first_indexed | 2024-03-13T02:23:30Z |
| format | Article |
| id | doaj.art-d772380453cf4050b65d34f087f4519e |
| institution | Directory Open Access Journal |
| issn | 2050-0904 |
| language | English |
| last_indexed | 2024-03-13T02:23:30Z |
| publishDate | 2023-06-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj.art-d772380453cf4050b65d34f087f4519e2023-06-30T07:34:07ZengWileyClinical Case Reports2050-09042023-06-01116n/an/a10.1002/ccr3.7409A case of MDS/MPN overlap syndrome with ring sideroblasts and thrombocytosis: Tackling the quandary of thrombosis versus hemorrhageHannah Cherniawsky0Habib Moshref Razavi1Division of Haematology, Department of Medicine University of British Columbia Vancouver British Columbia CanadaDivision of Hematopathology and Transfusion Medicine, Fraser Health Authority University of British Columbia Vancouver British Columbia CanadaKey Clinical Message No formal treatment guidelines for MDS/MPN‐RS‐T exist. With salient features such as anemia and thrombocytosis, management is individualized and aims to address anemia, thrombosis, and in some cases acquired von Willebrand's disease. Abstract Myelodysplastic/myeloproliferative overlap syndrome with ring sideroblasts and thrombocytosis (MDS/MPN‐RS‐T) is a rare myeloid neoplasm showing myelodysplastic and myeloproliferative features. With extremely raised platelets, possibility of acquired von Willebrand and risk of hemorrhage is increased. With this quandary in mind, a descriptive case and a brief discussion of available treatments ensues.https://doi.org/10.1002/ccr3.7409myelodysplastic/myeloproliferative overlap disordersring sideroblastssplicing factor 3b subunit 1 |
| spellingShingle | Hannah Cherniawsky Habib Moshref Razavi A case of MDS/MPN overlap syndrome with ring sideroblasts and thrombocytosis: Tackling the quandary of thrombosis versus hemorrhage Clinical Case Reports myelodysplastic/myeloproliferative overlap disorders ring sideroblasts splicing factor 3b subunit 1 |
| title | A case of MDS/MPN overlap syndrome with ring sideroblasts and thrombocytosis: Tackling the quandary of thrombosis versus hemorrhage |
| title_full | A case of MDS/MPN overlap syndrome with ring sideroblasts and thrombocytosis: Tackling the quandary of thrombosis versus hemorrhage |
| title_fullStr | A case of MDS/MPN overlap syndrome with ring sideroblasts and thrombocytosis: Tackling the quandary of thrombosis versus hemorrhage |
| title_full_unstemmed | A case of MDS/MPN overlap syndrome with ring sideroblasts and thrombocytosis: Tackling the quandary of thrombosis versus hemorrhage |
| title_short | A case of MDS/MPN overlap syndrome with ring sideroblasts and thrombocytosis: Tackling the quandary of thrombosis versus hemorrhage |
| title_sort | case of mds mpn overlap syndrome with ring sideroblasts and thrombocytosis tackling the quandary of thrombosis versus hemorrhage |
| topic | myelodysplastic/myeloproliferative overlap disorders ring sideroblasts splicing factor 3b subunit 1 |
| url | https://doi.org/10.1002/ccr3.7409 |
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