Allogeneic “Zombie Cell” as Off‐The‐Shelf Vaccine for Postsurgical Cancer Immunotherapy

Allogeneic “Zombie Cell” as Off‐The‐Shelf Vaccine for Postsurgical Cancer Immunotherapy

Abstract Allogeneic tumor cell vaccines provide off‐the‐shelf convenience but lack patient specificity due to heterogeneity in tumor antigens. Here, allogeneic tumor cell corpses are converted into “zombie cells” capable of assimilating heterogeneous tumor by seizing cancer cells and spreading adjuv...

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Bibliographic Details
Main Authors: Bo Li, Ping Zhang, Junlin Li, Rui Zhou, Minglu Zhou, Chendong Liu, Xi Liu, Liqiang Chen, Lian Li
Format: Article
Language:English
Published: Wiley 2024-04-01
Series:Advanced Science
Subjects:
biomedical engineering
cell delivery
localized therapy
postsurgical immunotherapy
whole tumor cell vaccine
Online Access:https://doi.org/10.1002/advs.202307030

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