Preoperative prognostic nutritional index as a predictive factor for medical complication after cervical posterior decompression surgery: A multicenter study

Study design: Retrospective longitudinal cohort study. Objective: To investigate postoperative medical complications in patients with malnutrition after cervical posterior surgery. Methods: A total of 256 patients were participated and divided into PNI < 50 group (group L) or PNI ≥ 50 (group H)....

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Main Authors: Kenta Kurosu, Shin Oe, Tomohiko Hasegawa, Satoshi Shimizu, Go Yoshida, Sho Kobayashi, Tomotada Fujita, Tomohiro Yamada, Koichiro Ide, Yuh Watanabe, Keiichi Nakai, Yu Yamato, Tatsuya Yasuda, Tomohiro Banno, Hideyuki Arima, Yuki Mihara, Hiroki Ushirozako, Yukihiro Matsuyama
Format: Article
Language:English
Published: SAGE Publishing 2021-04-01
Series:Journal of Orthopaedic Surgery
Online Access:https://doi.org/10.1177/23094990211006869
Description
Summary:Study design: Retrospective longitudinal cohort study. Objective: To investigate postoperative medical complications in patients with malnutrition after cervical posterior surgery. Methods: A total of 256 patients were participated and divided into PNI < 50 group (group L) or PNI ≥ 50 (group H). Patient data, preoperative laboratory data, surgical data, hospitalization data, JOA score, complication data were measured. Results: Group L and group H were 127 and 129 patients, each PNI was L: 44.8 ± 4.3, H: 54.6 ± 4.0, P < 0.01. There was significant difference in mean age (L: 72.2 years vs H: 64.8 years, P < 0.01), BMI (23.1 vs 24.7, P < 0.01), serum albumin (L: 3.9 ± 0.4 g/dl vs H: 4.4 ± 0.3 g/dl, P < 0.01), total lymphocyte count (L: 1.3 ± 0.5 10 3 /µL vs H: 2.1 ± 0.7 10 3 /μL, P < 0.01), hospital stay (L: 25.0 days vs H: 18.8 days, P < 0.05), discharge to home (87.5% vs 57.5%, P < 0.01), delirium (L: 15.9% vs H: 3.9%, P < 0.01), medical complications (L: 25.2% vs H: 7.0%, P < 0.01), pre- and post- operative JOA score (L: 11.3 ± 2.8 vs H: 12.4 ± 2.6, P < 0.01; L: 13.3 ± 3.0 vs H: 14.1 ± 2.4, P = 0.02). Multiple logistic regression analysis showed that significant risk factors for medical complications were PNI<50 (P = 0.024, odds ratio [OR] 2.746, 95% confidence interval [CI] 1.143–6.600) and age (P = 0.005, odds ratio [OR] 1.064, 95% confidence interval [CI] 1.020–1.111). Conclusion: Medical complications are significantly higher in patients with PNI < 50 and higher age. The results showed that PNI is a good indicator for perioperative medical complications in cervical posterior surgery. Improvement of preoperative nutritional status is important to avoid medical complications. Level of evidence: 3
ISSN:2309-4990