Correlation between IL 6 level and syetem-complications following multiple trauma in patients with blunt abdominal injuries
Severe trauma is the third cause of death and the first one in the most vital and young population. In USA more children die of trauma then of all other causes. Blunt abdominal trauma takes 56 % cases of multiple traumas of all etiologies. Among multiple injured patients, near to 50 % have some syst...
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| Format: | Article |
| Language: | English |
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Serbian Medical Society
2003-01-01
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| Series: | Srpski Arhiv za Celokupno Lekarstvo |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0370-8179/2003/0370-81790304118G.pdf |
| _version_ | 1818886743120674816 |
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| author | Gregorić Pavle D. Bajec Đorđe D. Šijački Ana D. Karadžić Borivoje A. |
| author_facet | Gregorić Pavle D. Bajec Đorđe D. Šijački Ana D. Karadžić Borivoje A. |
| author_sort | Gregorić Pavle D. |
| collection | DOAJ |
| description | Severe trauma is the third cause of death and the first one in the most vital and young population. In USA more children die of trauma then of all other causes. Blunt abdominal trauma takes 56 % cases of multiple traumas of all etiologies. Among multiple injured patients, near to 50 % have some system-complications, more of 60 % in the group of critically injured (ISS>35). Cytokines play the main role in the inflammatory reaction during the early phase response on trauma. Their secretion predicts system-complications as ARDS, SIRS, even MODS. Hypothetically, level of concentration of Interleukin-6 (IL 6) can improve methods of early diagnostic procedures for detecting SIRS and MODS, when scores are still low (preclinical level), at which stages therapy is more powerful and also cheaper. This prospective study includes 35 multiple injured persons with blunt abdominal trauma (75>ISS>18). We have used standard diagnostic procedures. Concentration of IL 6 was detected with ELISA-test. Levels of IL 6 were significantly higher in correlation with SIRS score groups. Correlation with MODS score was not significant for the lowest scores, but IL 6 showed significant higher levels in the second and the third MODS score group. |
| first_indexed | 2024-12-19T16:26:11Z |
| format | Article |
| id | doaj.art-d776e44badf043babb7b689487fb3d86 |
| institution | Directory Open Access Journal |
| issn | 0370-8179 |
| language | English |
| last_indexed | 2024-12-19T16:26:11Z |
| publishDate | 2003-01-01 |
| publisher | Serbian Medical Society |
| record_format | Article |
| series | Srpski Arhiv za Celokupno Lekarstvo |
| spelling | doaj.art-d776e44badf043babb7b689487fb3d862022-12-21T20:14:21ZengSerbian Medical SocietySrpski Arhiv za Celokupno Lekarstvo0370-81792003-01-011313-411812110.2298/SARH0304118GCorrelation between IL 6 level and syetem-complications following multiple trauma in patients with blunt abdominal injuriesGregorić Pavle D.Bajec Đorđe D.Šijački Ana D.Karadžić Borivoje A.Severe trauma is the third cause of death and the first one in the most vital and young population. In USA more children die of trauma then of all other causes. Blunt abdominal trauma takes 56 % cases of multiple traumas of all etiologies. Among multiple injured patients, near to 50 % have some system-complications, more of 60 % in the group of critically injured (ISS>35). Cytokines play the main role in the inflammatory reaction during the early phase response on trauma. Their secretion predicts system-complications as ARDS, SIRS, even MODS. Hypothetically, level of concentration of Interleukin-6 (IL 6) can improve methods of early diagnostic procedures for detecting SIRS and MODS, when scores are still low (preclinical level), at which stages therapy is more powerful and also cheaper. This prospective study includes 35 multiple injured persons with blunt abdominal trauma (75>ISS>18). We have used standard diagnostic procedures. Concentration of IL 6 was detected with ELISA-test. Levels of IL 6 were significantly higher in correlation with SIRS score groups. Correlation with MODS score was not significant for the lowest scores, but IL 6 showed significant higher levels in the second and the third MODS score group.http://www.doiserbia.nb.rs/img/doi/0370-8179/2003/0370-81790304118G.pdfmultiple traumablunt abdominal traumaInterleukin-6complications |
| spellingShingle | Gregorić Pavle D. Bajec Đorđe D. Šijački Ana D. Karadžić Borivoje A. Correlation between IL 6 level and syetem-complications following multiple trauma in patients with blunt abdominal injuries Srpski Arhiv za Celokupno Lekarstvo multiple trauma blunt abdominal trauma Interleukin-6 complications |
| title | Correlation between IL 6 level and syetem-complications following multiple trauma in patients with blunt abdominal injuries |
| title_full | Correlation between IL 6 level and syetem-complications following multiple trauma in patients with blunt abdominal injuries |
| title_fullStr | Correlation between IL 6 level and syetem-complications following multiple trauma in patients with blunt abdominal injuries |
| title_full_unstemmed | Correlation between IL 6 level and syetem-complications following multiple trauma in patients with blunt abdominal injuries |
| title_short | Correlation between IL 6 level and syetem-complications following multiple trauma in patients with blunt abdominal injuries |
| title_sort | correlation between il 6 level and syetem complications following multiple trauma in patients with blunt abdominal injuries |
| topic | multiple trauma blunt abdominal trauma Interleukin-6 complications |
| url | http://www.doiserbia.nb.rs/img/doi/0370-8179/2003/0370-81790304118G.pdf |
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