Interaction of Water-Soluble CdTe Quantum Dots with Bovine Serum Albumin

<p>Abstract</p> <p>Semiconductor nanoparticles (quantum dots) are promising fluorescent markers, but it is very little known about interaction of quantum dots with biological molecules. In this study, interaction of CdTe quantum dots coated with thioglycolic acid (TGA) with bovine...

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Main Authors: Matulionyte Marija, Selskis Algirdas, Poderys Vilius, Rotomskis Ricardas
Format: Article
Language:English
Published: SpringerOpen 2011-01-01
Series:Nanoscale Research Letters
Subjects:
Online Access:http://www.nanoscalereslett.com/content/6/1/9
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author Matulionyte Marija
Selskis Algirdas
Poderys Vilius
Rotomskis Ricardas
author_facet Matulionyte Marija
Selskis Algirdas
Poderys Vilius
Rotomskis Ricardas
author_sort Matulionyte Marija
collection DOAJ
description <p>Abstract</p> <p>Semiconductor nanoparticles (quantum dots) are promising fluorescent markers, but it is very little known about interaction of quantum dots with biological molecules. In this study, interaction of CdTe quantum dots coated with thioglycolic acid (TGA) with bovine serum albumin was investigated. Steady state spectroscopy, atomic force microscopy, electron microscopy and dynamic light scattering methods were used. It was explored how bovine serum albumin affects stability and spectral properties of quantum dots in aqueous media. CdTe&#8211;TGA quantum dots in aqueous solution appeared to be not stable and precipitated. Interaction with bovine serum albumin significantly enhanced stability and photoluminescence quantum yield of quantum dots and prevented quantum dots from aggregating.</p>
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spelling doaj.art-d778710be71e498786448310e7344ece2023-09-02T14:57:58ZengSpringerOpenNanoscale Research Letters1931-75731556-276X2011-01-01619Interaction of Water-Soluble CdTe Quantum Dots with Bovine Serum AlbuminMatulionyte MarijaSelskis AlgirdasPoderys ViliusRotomskis Ricardas<p>Abstract</p> <p>Semiconductor nanoparticles (quantum dots) are promising fluorescent markers, but it is very little known about interaction of quantum dots with biological molecules. In this study, interaction of CdTe quantum dots coated with thioglycolic acid (TGA) with bovine serum albumin was investigated. Steady state spectroscopy, atomic force microscopy, electron microscopy and dynamic light scattering methods were used. It was explored how bovine serum albumin affects stability and spectral properties of quantum dots in aqueous media. CdTe&#8211;TGA quantum dots in aqueous solution appeared to be not stable and precipitated. Interaction with bovine serum albumin significantly enhanced stability and photoluminescence quantum yield of quantum dots and prevented quantum dots from aggregating.</p>http://www.nanoscalereslett.com/content/6/1/9Quantum dotsAggregationBovine serum albuminInteractionStabilization
spellingShingle Matulionyte Marija
Selskis Algirdas
Poderys Vilius
Rotomskis Ricardas
Interaction of Water-Soluble CdTe Quantum Dots with Bovine Serum Albumin
Nanoscale Research Letters
Quantum dots
Aggregation
Bovine serum albumin
Interaction
Stabilization
title Interaction of Water-Soluble CdTe Quantum Dots with Bovine Serum Albumin
title_full Interaction of Water-Soluble CdTe Quantum Dots with Bovine Serum Albumin
title_fullStr Interaction of Water-Soluble CdTe Quantum Dots with Bovine Serum Albumin
title_full_unstemmed Interaction of Water-Soluble CdTe Quantum Dots with Bovine Serum Albumin
title_short Interaction of Water-Soluble CdTe Quantum Dots with Bovine Serum Albumin
title_sort interaction of water soluble cdte quantum dots with bovine serum albumin
topic Quantum dots
Aggregation
Bovine serum albumin
Interaction
Stabilization
url http://www.nanoscalereslett.com/content/6/1/9
work_keys_str_mv AT matulionytemarija interactionofwatersolublecdtequantumdotswithbovineserumalbumin
AT selskisalgirdas interactionofwatersolublecdtequantumdotswithbovineserumalbumin
AT poderysvilius interactionofwatersolublecdtequantumdotswithbovineserumalbumin
AT rotomskisricardas interactionofwatersolublecdtequantumdotswithbovineserumalbumin