Interaction of Water-Soluble CdTe Quantum Dots with Bovine Serum Albumin
<p>Abstract</p> <p>Semiconductor nanoparticles (quantum dots) are promising fluorescent markers, but it is very little known about interaction of quantum dots with biological molecules. In this study, interaction of CdTe quantum dots coated with thioglycolic acid (TGA) with bovine...
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Format: | Article |
Language: | English |
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SpringerOpen
2011-01-01
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Series: | Nanoscale Research Letters |
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Online Access: | http://www.nanoscalereslett.com/content/6/1/9 |
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author | Matulionyte Marija Selskis Algirdas Poderys Vilius Rotomskis Ricardas |
author_facet | Matulionyte Marija Selskis Algirdas Poderys Vilius Rotomskis Ricardas |
author_sort | Matulionyte Marija |
collection | DOAJ |
description | <p>Abstract</p> <p>Semiconductor nanoparticles (quantum dots) are promising fluorescent markers, but it is very little known about interaction of quantum dots with biological molecules. In this study, interaction of CdTe quantum dots coated with thioglycolic acid (TGA) with bovine serum albumin was investigated. Steady state spectroscopy, atomic force microscopy, electron microscopy and dynamic light scattering methods were used. It was explored how bovine serum albumin affects stability and spectral properties of quantum dots in aqueous media. CdTe–TGA quantum dots in aqueous solution appeared to be not stable and precipitated. Interaction with bovine serum albumin significantly enhanced stability and photoluminescence quantum yield of quantum dots and prevented quantum dots from aggregating.</p> |
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format | Article |
id | doaj.art-d778710be71e498786448310e7344ece |
institution | Directory Open Access Journal |
issn | 1931-7573 1556-276X |
language | English |
last_indexed | 2024-03-12T09:12:16Z |
publishDate | 2011-01-01 |
publisher | SpringerOpen |
record_format | Article |
series | Nanoscale Research Letters |
spelling | doaj.art-d778710be71e498786448310e7344ece2023-09-02T14:57:58ZengSpringerOpenNanoscale Research Letters1931-75731556-276X2011-01-01619Interaction of Water-Soluble CdTe Quantum Dots with Bovine Serum AlbuminMatulionyte MarijaSelskis AlgirdasPoderys ViliusRotomskis Ricardas<p>Abstract</p> <p>Semiconductor nanoparticles (quantum dots) are promising fluorescent markers, but it is very little known about interaction of quantum dots with biological molecules. In this study, interaction of CdTe quantum dots coated with thioglycolic acid (TGA) with bovine serum albumin was investigated. Steady state spectroscopy, atomic force microscopy, electron microscopy and dynamic light scattering methods were used. It was explored how bovine serum albumin affects stability and spectral properties of quantum dots in aqueous media. CdTe–TGA quantum dots in aqueous solution appeared to be not stable and precipitated. Interaction with bovine serum albumin significantly enhanced stability and photoluminescence quantum yield of quantum dots and prevented quantum dots from aggregating.</p>http://www.nanoscalereslett.com/content/6/1/9Quantum dotsAggregationBovine serum albuminInteractionStabilization |
spellingShingle | Matulionyte Marija Selskis Algirdas Poderys Vilius Rotomskis Ricardas Interaction of Water-Soluble CdTe Quantum Dots with Bovine Serum Albumin Nanoscale Research Letters Quantum dots Aggregation Bovine serum albumin Interaction Stabilization |
title | Interaction of Water-Soluble CdTe Quantum Dots with Bovine Serum Albumin |
title_full | Interaction of Water-Soluble CdTe Quantum Dots with Bovine Serum Albumin |
title_fullStr | Interaction of Water-Soluble CdTe Quantum Dots with Bovine Serum Albumin |
title_full_unstemmed | Interaction of Water-Soluble CdTe Quantum Dots with Bovine Serum Albumin |
title_short | Interaction of Water-Soluble CdTe Quantum Dots with Bovine Serum Albumin |
title_sort | interaction of water soluble cdte quantum dots with bovine serum albumin |
topic | Quantum dots Aggregation Bovine serum albumin Interaction Stabilization |
url | http://www.nanoscalereslett.com/content/6/1/9 |
work_keys_str_mv | AT matulionytemarija interactionofwatersolublecdtequantumdotswithbovineserumalbumin AT selskisalgirdas interactionofwatersolublecdtequantumdotswithbovineserumalbumin AT poderysvilius interactionofwatersolublecdtequantumdotswithbovineserumalbumin AT rotomskisricardas interactionofwatersolublecdtequantumdotswithbovineserumalbumin |