Evolutionary patterns of phosphorylated serines
<p>Abstract</p> <p/> <p>Posttranslationally modified amino acids are chemically distinct types of amino acids and in terms of evolution they might behave differently from their non-modified counterparts. In order to check this possibility, we reconstructed the evolutionary hi...
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| Format: | Article |
| Language: | English |
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BMC
2011-02-01
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| Series: | Biology Direct |
| Online Access: | http://www.biology-direct.com/content/6/1/8 |
| _version_ | 1819042372006182912 |
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| author | Goland Alexander Kurmangaliyev Yerbol Z Gelfand Mikhail S |
| author_facet | Goland Alexander Kurmangaliyev Yerbol Z Gelfand Mikhail S |
| author_sort | Goland Alexander |
| collection | DOAJ |
| description | <p>Abstract</p> <p/> <p>Posttranslationally modified amino acids are chemically distinct types of amino acids and in terms of evolution they might behave differently from their non-modified counterparts. In order to check this possibility, we reconstructed the evolutionary history of phosphorylated serines in several groups of organisms. Comparisons of substitution vectors have revealed some significant differences in the evolution of modified and corresponding non-modified amino acids. In particular, phosphoserines are more frequently substituted to aspartate and glutamate, compared to non-phosphorylated serines.</p> <p>Reviewers</p> <p>This article was reviewed by Arcady Mushegian and Sandor Pongor.</p> |
| first_indexed | 2024-12-21T09:39:50Z |
| format | Article |
| id | doaj.art-d779ac2262b245e4a1b8c624b0dc4c16 |
| institution | Directory Open Access Journal |
| issn | 1745-6150 |
| language | English |
| last_indexed | 2024-12-21T09:39:50Z |
| publishDate | 2011-02-01 |
| publisher | BMC |
| record_format | Article |
| series | Biology Direct |
| spelling | doaj.art-d779ac2262b245e4a1b8c624b0dc4c162022-12-21T19:08:31ZengBMCBiology Direct1745-61502011-02-0161810.1186/1745-6150-6-8Evolutionary patterns of phosphorylated serinesGoland AlexanderKurmangaliyev Yerbol ZGelfand Mikhail S<p>Abstract</p> <p/> <p>Posttranslationally modified amino acids are chemically distinct types of amino acids and in terms of evolution they might behave differently from their non-modified counterparts. In order to check this possibility, we reconstructed the evolutionary history of phosphorylated serines in several groups of organisms. Comparisons of substitution vectors have revealed some significant differences in the evolution of modified and corresponding non-modified amino acids. In particular, phosphoserines are more frequently substituted to aspartate and glutamate, compared to non-phosphorylated serines.</p> <p>Reviewers</p> <p>This article was reviewed by Arcady Mushegian and Sandor Pongor.</p>http://www.biology-direct.com/content/6/1/8 |
| spellingShingle | Goland Alexander Kurmangaliyev Yerbol Z Gelfand Mikhail S Evolutionary patterns of phosphorylated serines Biology Direct |
| title | Evolutionary patterns of phosphorylated serines |
| title_full | Evolutionary patterns of phosphorylated serines |
| title_fullStr | Evolutionary patterns of phosphorylated serines |
| title_full_unstemmed | Evolutionary patterns of phosphorylated serines |
| title_short | Evolutionary patterns of phosphorylated serines |
| title_sort | evolutionary patterns of phosphorylated serines |
| url | http://www.biology-direct.com/content/6/1/8 |
| work_keys_str_mv | AT golandalexander evolutionarypatternsofphosphorylatedserines AT kurmangaliyevyerbolz evolutionarypatternsofphosphorylatedserines AT gelfandmikhails evolutionarypatternsofphosphorylatedserines |