Morphological analysis of a structures of prenatal pancreas in human
As a mixed exocrine and endocrine gland pancreas has a very important role in the digestive tract. The juice of his exocrine part, which is released into the duodenum, carries more than 20 pancreatic enzymes, important for a normal process of digestion. Endocrine part of the gland, which consists of...
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| Format: | Article |
| Language: | English |
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Medicinski fakultet Priština, Društvo lekara Kosova i Metohije Srpskog lekarskog društva
2016-01-01
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| Series: | Praxis Medica |
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| Online Access: | http://scindeks-clanci.ceon.rs/data/pdf/0350-8773/2016/0350-87731601005F.pdf |
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| author | Filipović Tatjana Filipović Milan Mandić Predrag Matejić Suzana Đukić Nataša Vitošević Zdravko |
| author_facet | Filipović Tatjana Filipović Milan Mandić Predrag Matejić Suzana Đukić Nataša Vitošević Zdravko |
| author_sort | Filipović Tatjana |
| collection | DOAJ |
| description | As a mixed exocrine and endocrine gland pancreas has a very important role in the digestive tract. The juice of his exocrine part, which is released into the duodenum, carries more than 20 pancreatic enzymes, important for a normal process of digestion. Endocrine part of the gland, which consists of the islets-insula, actively participate in the metabolism of human organism, secreting two important hormones - insulin and glucagon. Because of its location, the pancreas is an extremely inaccessible organ for a physical examination. Despite of a large number of modern clinical methods for monitoring changes in the body, the detail knowledge of morphological characteristics of this gland is still very important. The material was taken from the cadaver of the fetus and newborn at the Institute of Pathology of the Faculty of Medicine. We classified samples of pancreas into three groups, with respect to age (from 3 months to neonates) and CS length. After dehydration and the molding compositions are cut at a thickness of between 6 and 10 microns. In addition to standard staining methods, some preparations are for identification of insula, painted by Grimelijus. In this study, we determined the morphological changes of the prenatal pancreas, from the third month of intrauterine fetal development, until the end of the fetal time and determine the dynamics of changes in the parenchyma and stroma. We could distinguish functional parts of the pancreas, in 10-11th week of development. In the first trimester of pregnancy, we have noticed an increase in parenchymal elements and the reduction of the stroma, which is slightly more pronounced in interlobular area, that clearly differentiating lobules. At the beginning of the second trimester of pregnancy, in the pancreas that are developing, we observed significant changes. The lobular structure of pancreas was clearly visible. Pancreatic acini are clearly differentiated and are in very close contact, since the stroma between them very reduced. Within almost all lobulus there are clearly expressed the islets of Langerhans, which are multiplied, different sizes, separated from the exocrine part by poorly expressed connective tissue. In the group of prematurely born children, we found that the morphology of the pancreas is very similar to the pancreas at the end of the fetal period. |
| first_indexed | 2024-04-12T04:22:45Z |
| format | Article |
| id | doaj.art-d77cb7dfd279452daa2aa56e488274f3 |
| institution | Directory Open Access Journal |
| issn | 0350-8773 |
| language | English |
| last_indexed | 2024-04-12T04:22:45Z |
| publishDate | 2016-01-01 |
| publisher | Medicinski fakultet Priština, Društvo lekara Kosova i Metohije Srpskog lekarskog društva |
| record_format | Article |
| series | Praxis Medica |
| spelling | doaj.art-d77cb7dfd279452daa2aa56e488274f32022-12-22T03:48:11ZengMedicinski fakultet Priština, Društvo lekara Kosova i Metohije Srpskog lekarskog društvaPraxis Medica0350-87732016-01-014515910.5937/pramed1601005F0350-87731601005FMorphological analysis of a structures of prenatal pancreas in humanFilipović Tatjana0Filipović Milan1Mandić Predrag2Matejić Suzana3Đukić Nataša4Vitošević Zdravko5Institut za anatomiju, Medicinski fakultet, Priština-Kosovska MitrovicaKlinika za hirurgiju, Medicinski fakultet, Priština-Kosovska MitrovicaInstitut za anatomiju, Medicinski fakultet, Priština-Kosovska MitrovicaInstitut za sudsku medicinu, Medicinski fakultet, Priština-Kosovska MitrovicaInstitut za anatomiju, Medicinski fakultet, Priština-Kosovska MitrovicaInstitut za anatomiju, Medicinski fakultet, Priština-Kosovska MitrovicaAs a mixed exocrine and endocrine gland pancreas has a very important role in the digestive tract. The juice of his exocrine part, which is released into the duodenum, carries more than 20 pancreatic enzymes, important for a normal process of digestion. Endocrine part of the gland, which consists of the islets-insula, actively participate in the metabolism of human organism, secreting two important hormones - insulin and glucagon. Because of its location, the pancreas is an extremely inaccessible organ for a physical examination. Despite of a large number of modern clinical methods for monitoring changes in the body, the detail knowledge of morphological characteristics of this gland is still very important. The material was taken from the cadaver of the fetus and newborn at the Institute of Pathology of the Faculty of Medicine. We classified samples of pancreas into three groups, with respect to age (from 3 months to neonates) and CS length. After dehydration and the molding compositions are cut at a thickness of between 6 and 10 microns. In addition to standard staining methods, some preparations are for identification of insula, painted by Grimelijus. In this study, we determined the morphological changes of the prenatal pancreas, from the third month of intrauterine fetal development, until the end of the fetal time and determine the dynamics of changes in the parenchyma and stroma. We could distinguish functional parts of the pancreas, in 10-11th week of development. In the first trimester of pregnancy, we have noticed an increase in parenchymal elements and the reduction of the stroma, which is slightly more pronounced in interlobular area, that clearly differentiating lobules. At the beginning of the second trimester of pregnancy, in the pancreas that are developing, we observed significant changes. The lobular structure of pancreas was clearly visible. Pancreatic acini are clearly differentiated and are in very close contact, since the stroma between them very reduced. Within almost all lobulus there are clearly expressed the islets of Langerhans, which are multiplied, different sizes, separated from the exocrine part by poorly expressed connective tissue. In the group of prematurely born children, we found that the morphology of the pancreas is very similar to the pancreas at the end of the fetal period.http://scindeks-clanci.ceon.rs/data/pdf/0350-8773/2016/0350-87731601005F.pdfPancreasstructuredevelopment |
| spellingShingle | Filipović Tatjana Filipović Milan Mandić Predrag Matejić Suzana Đukić Nataša Vitošević Zdravko Morphological analysis of a structures of prenatal pancreas in human Praxis Medica Pancreas structure development |
| title | Morphological analysis of a structures of prenatal pancreas in human |
| title_full | Morphological analysis of a structures of prenatal pancreas in human |
| title_fullStr | Morphological analysis of a structures of prenatal pancreas in human |
| title_full_unstemmed | Morphological analysis of a structures of prenatal pancreas in human |
| title_short | Morphological analysis of a structures of prenatal pancreas in human |
| title_sort | morphological analysis of a structures of prenatal pancreas in human |
| topic | Pancreas structure development |
| url | http://scindeks-clanci.ceon.rs/data/pdf/0350-8773/2016/0350-87731601005F.pdf |
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