Cardiac amyloidosis: a challenging diagnosis
Cardiovascular involvement of amyloidosis is present in 90% of cases, which is frequently associated with the primary form of the disease (AL amyloidosis). Clinical manifestations are represented by heart failure due to restrictive myocardiopathy and electrical impulse conduction abnormalities, whic...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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University of São Paulo
2014-12-01
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| Series: | Autopsy and Case Reports |
| Subjects: | |
| Online Access: | http://www.revistas.usp.br/autopsy/article/view/98461 |
| _version_ | 1811278572496617472 |
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| author | Graziele Cristina Palancio Morais Marjorie Moreira Arruda José Carlos de Aguiar Bonadia Geanete Pozzan |
| author_facet | Graziele Cristina Palancio Morais Marjorie Moreira Arruda José Carlos de Aguiar Bonadia Geanete Pozzan |
| author_sort | Graziele Cristina Palancio Morais |
| collection | DOAJ |
| description | Cardiovascular involvement of amyloidosis is present in 90% of cases, which is frequently associated with the primary form of the disease (AL amyloidosis). Clinical manifestations are represented by heart failure due to restrictive myocardiopathy and electrical impulse conduction abnormalities, which are clinically remarkable in up to 50% of the cases. The prognosis of patients with systemic amyloidosis is directly associated with the presence of cardiac involvement, such that survival does not usually exceed 4 months after the onset of heart failure signs and symptoms. The authors report a case of primary systemic amyloidosis, diagnosed only at autopsy, with severe cardiac involvement. |
| first_indexed | 2024-04-13T00:38:15Z |
| format | Article |
| id | doaj.art-d77dca8f1133498cadbcf691a55cbcf1 |
| institution | Directory Open Access Journal |
| issn | 2236-1960 |
| language | English |
| last_indexed | 2024-04-13T00:38:15Z |
| publishDate | 2014-12-01 |
| publisher | University of São Paulo |
| record_format | Article |
| series | Autopsy and Case Reports |
| spelling | doaj.art-d77dca8f1133498cadbcf691a55cbcf12022-12-22T03:10:16ZengUniversity of São PauloAutopsy and Case Reports2236-19602014-12-014410.4322/acr.%y.9846188479Cardiac amyloidosis: a challenging diagnosisGraziele Cristina Palancio Morais0Marjorie Moreira Arruda1José Carlos de Aguiar Bonadia2Geanete Pozzan3Department of Pathological Sciences – Faculdade de Ciências Médicas – Santa Casa de Misericórdia de São Paulo - São Paulo/SPDepartment of Pathological Sciences – Faculdade de Ciências Médicas – Santa Casa de Misericórdia de São Paulo - São Paulo/SPDepartment of Pathological Sciences – Faculdade de Ciências Médicas – Santa Casa de Misericórdia de São Paulo - São Paulo/SPDepartment of Pathological Sciences – Faculdade de Ciências Médicas – Santa Casa de Misericórdia de São Paulo - São Paulo/SPCardiovascular involvement of amyloidosis is present in 90% of cases, which is frequently associated with the primary form of the disease (AL amyloidosis). Clinical manifestations are represented by heart failure due to restrictive myocardiopathy and electrical impulse conduction abnormalities, which are clinically remarkable in up to 50% of the cases. The prognosis of patients with systemic amyloidosis is directly associated with the presence of cardiac involvement, such that survival does not usually exceed 4 months after the onset of heart failure signs and symptoms. The authors report a case of primary systemic amyloidosis, diagnosed only at autopsy, with severe cardiac involvement.http://www.revistas.usp.br/autopsy/article/view/98461AmyloidosisCardiomyopathyRestrictiveAutopsy |
| spellingShingle | Graziele Cristina Palancio Morais Marjorie Moreira Arruda José Carlos de Aguiar Bonadia Geanete Pozzan Cardiac amyloidosis: a challenging diagnosis Autopsy and Case Reports Amyloidosis Cardiomyopathy Restrictive Autopsy |
| title | Cardiac amyloidosis: a challenging diagnosis |
| title_full | Cardiac amyloidosis: a challenging diagnosis |
| title_fullStr | Cardiac amyloidosis: a challenging diagnosis |
| title_full_unstemmed | Cardiac amyloidosis: a challenging diagnosis |
| title_short | Cardiac amyloidosis: a challenging diagnosis |
| title_sort | cardiac amyloidosis a challenging diagnosis |
| topic | Amyloidosis Cardiomyopathy Restrictive Autopsy |
| url | http://www.revistas.usp.br/autopsy/article/view/98461 |
| work_keys_str_mv | AT grazielecristinapalanciomorais cardiacamyloidosisachallengingdiagnosis AT marjoriemoreiraarruda cardiacamyloidosisachallengingdiagnosis AT josecarlosdeaguiarbonadia cardiacamyloidosisachallengingdiagnosis AT geanetepozzan cardiacamyloidosisachallengingdiagnosis |