Primary ameloblastic carcinoma: literature review with case series
Ameloblastic carcinoma (AC) is an extremely rare malignant odontogenic tumour arising from odontogenic epithelium. It was classified into primary type and secondary type. A previous study revealed that primary ameloblastic carcinoma cases were associated with more favourable prognosis than secondary...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Termedia Publishing House
2018-11-01
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| Series: | Polish Journal of Pathology |
| Subjects: | |
| Online Access: | https://www.termedia.pl/Primary-ameloblastic-carcinoma-literature-review-with-case-series,55,34114,1,1.html |
| _version_ | 1818302865966366720 |
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| author | Sarah Ahmed Mohamed Mahmoud Hatem Wael Amer Sally Ibrahim Mohamed |
| author_facet | Sarah Ahmed Mohamed Mahmoud Hatem Wael Amer Sally Ibrahim Mohamed |
| author_sort | Sarah Ahmed Mohamed Mahmoud |
| collection | DOAJ |
| description | Ameloblastic carcinoma (AC) is an extremely rare malignant odontogenic tumour arising from odontogenic epithelium. It was classified into primary type and secondary type. A previous study revealed that primary ameloblastic carcinoma cases were associated with more favourable prognosis than secondary cases. The aim of the present work was: to report the clinical, histopathological, immunohistochemical, and ploidy status, and therapeutic details of four cases of primary AC, and to review the literature with regard to clinical, follow-up, prognosis, histopathological, and immunohistochemical information of primary AC. The Medline database was searched using the term ameloblastic carcinoma and primary type. The review of English literature revealed that primary ameloblastic carcinoma favours the posterior mandible with profound male predilection and appears as an ill-defined radiolucency. Metastasis and invasion are more likely to occur in maxillary cases. The treatment of choice is wide surgical resection with or without cervical lymph node dissection. Adjuvant postoperative radiotherapy is beneficial in incomplete resection cases and advanced soft tissue invasion. The most specific diagnostic methods of AC, as concluded from review, are α-SMA in epithelial cells in conjunction with Ki-67 index value and SPF more than 11.5%. |
| first_indexed | 2024-12-13T05:45:42Z |
| format | Article |
| id | doaj.art-d7802d092a004d83a31a36b59be37727 |
| institution | Directory Open Access Journal |
| issn | 1233-9687 2084-9869 |
| language | English |
| last_indexed | 2024-12-13T05:45:42Z |
| publishDate | 2018-11-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Polish Journal of Pathology |
| spelling | doaj.art-d7802d092a004d83a31a36b59be377272022-12-21T23:57:40ZengTermedia Publishing HousePolish Journal of Pathology1233-96872084-98692018-11-0169324325310.5114/pjp.2018.7954434114Primary ameloblastic carcinoma: literature review with case seriesSarah Ahmed Mohamed MahmoudHatem Wael AmerSally Ibrahim MohamedAmeloblastic carcinoma (AC) is an extremely rare malignant odontogenic tumour arising from odontogenic epithelium. It was classified into primary type and secondary type. A previous study revealed that primary ameloblastic carcinoma cases were associated with more favourable prognosis than secondary cases. The aim of the present work was: to report the clinical, histopathological, immunohistochemical, and ploidy status, and therapeutic details of four cases of primary AC, and to review the literature with regard to clinical, follow-up, prognosis, histopathological, and immunohistochemical information of primary AC. The Medline database was searched using the term ameloblastic carcinoma and primary type. The review of English literature revealed that primary ameloblastic carcinoma favours the posterior mandible with profound male predilection and appears as an ill-defined radiolucency. Metastasis and invasion are more likely to occur in maxillary cases. The treatment of choice is wide surgical resection with or without cervical lymph node dissection. Adjuvant postoperative radiotherapy is beneficial in incomplete resection cases and advanced soft tissue invasion. The most specific diagnostic methods of AC, as concluded from review, are α-SMA in epithelial cells in conjunction with Ki-67 index value and SPF more than 11.5%.https://www.termedia.pl/Primary-ameloblastic-carcinoma-literature-review-with-case-series,55,34114,1,1.htmlameloblastic carcinoma case series primary type review |
| spellingShingle | Sarah Ahmed Mohamed Mahmoud Hatem Wael Amer Sally Ibrahim Mohamed Primary ameloblastic carcinoma: literature review with case series Polish Journal of Pathology ameloblastic carcinoma case series primary type review |
| title | Primary ameloblastic carcinoma: literature review with case series |
| title_full | Primary ameloblastic carcinoma: literature review with case series |
| title_fullStr | Primary ameloblastic carcinoma: literature review with case series |
| title_full_unstemmed | Primary ameloblastic carcinoma: literature review with case series |
| title_short | Primary ameloblastic carcinoma: literature review with case series |
| title_sort | primary ameloblastic carcinoma literature review with case series |
| topic | ameloblastic carcinoma case series primary type review |
| url | https://www.termedia.pl/Primary-ameloblastic-carcinoma-literature-review-with-case-series,55,34114,1,1.html |
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