Protocol for a systematic review of substance use and misuse prevalence and associated factors among transgender and non-binary youth living in the USA
Background Transgender and gender non-binary (TNB) youth living in the USA report elevated levels of substance use compared with their cisgender counterparts, with previous literature pointing to minority stressors as some of the factors that could facilitate such elevated levels. Yet, substance use...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMJ Publishing Group
2023-08-01
|
| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/13/8/e073877.full |
| _version_ | 1797730349842694144 |
|---|---|
| author | Darren L Whitfield Tural Mammadli Gail Betz Linda-Jeanne M Mack |
| author_facet | Darren L Whitfield Tural Mammadli Gail Betz Linda-Jeanne M Mack |
| author_sort | Darren L Whitfield |
| collection | DOAJ |
| description | Background Transgender and gender non-binary (TNB) youth living in the USA report elevated levels of substance use compared with their cisgender counterparts, with previous literature pointing to minority stressors as some of the factors that could facilitate such elevated levels. Yet, substance use and misuse prevalence and associated modifiable factors among TNB youth are not fully known. The current paper details the protocol for a systematic review aimed at (1) identifying substance use and misuse prevalence among TNB youth (ages <25) and related demographic disparities (based on racial, ethnic and gender identity, and sexual orientation), (2) examining factors associated with substance use and misuse among TNB youth and (3) examining protective factors against substance use and misuse among TNB youth.Methods and analysis Systematic searches will be conducted across four databases: PubMed, LGBTQ+ Source, CINAHL and PsycInfo to identify quantitative, qualitative and mixed-methods peer-reviewed research publications. An exhaustive list of keywords and corresponding MeSH (Medical Subject Headings) terms representing the concepts of ‘TNB’ (the population of interest) and ‘substance use and misuse’ (outcome) will be employed. Identified records will be initially screened via a review of titles and abstracts. Full text of the remaining records will be reviewed corresponding to the inclusion and exclusion criteria. Extracted data will be synthesised in table and narrative format. A meta-analysis will be considered contingent on the existence of sufficient data. Methodological quality and risk of bias of studies will be assessed.Ethics and dissemination This review does not require approval from the Institutional Review Board as it involves no interactions with human subjects. We will disseminate our findings via peer-reviewed manuscripts and academic conference presentations.PROSPERO registration number CRD42023394985. |
| first_indexed | 2024-03-12T11:43:00Z |
| format | Article |
| id | doaj.art-d7811804eb5b4fe2a733492372560634 |
| institution | Directory Open Access Journal |
| issn | 2044-6055 |
| language | English |
| last_indexed | 2024-03-12T11:43:00Z |
| publishDate | 2023-08-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj.art-d7811804eb5b4fe2a7334923725606342023-08-31T13:30:07ZengBMJ Publishing GroupBMJ Open2044-60552023-08-0113810.1136/bmjopen-2023-073877Protocol for a systematic review of substance use and misuse prevalence and associated factors among transgender and non-binary youth living in the USADarren L Whitfield0Tural Mammadli1Gail Betz2Linda-Jeanne M Mack3School of Social Work, University of Maryland, Baltimore, Maryland, USASchool of Social Work, University of Maryland, Baltimore, Maryland, USAHealth Sciences and Human Services Library, University of Maryland Baltimore, Baltimore, Maryland, USASchool of Social Work, University of Maryland Baltimore, Baltimore, Maryland, USABackground Transgender and gender non-binary (TNB) youth living in the USA report elevated levels of substance use compared with their cisgender counterparts, with previous literature pointing to minority stressors as some of the factors that could facilitate such elevated levels. Yet, substance use and misuse prevalence and associated modifiable factors among TNB youth are not fully known. The current paper details the protocol for a systematic review aimed at (1) identifying substance use and misuse prevalence among TNB youth (ages <25) and related demographic disparities (based on racial, ethnic and gender identity, and sexual orientation), (2) examining factors associated with substance use and misuse among TNB youth and (3) examining protective factors against substance use and misuse among TNB youth.Methods and analysis Systematic searches will be conducted across four databases: PubMed, LGBTQ+ Source, CINAHL and PsycInfo to identify quantitative, qualitative and mixed-methods peer-reviewed research publications. An exhaustive list of keywords and corresponding MeSH (Medical Subject Headings) terms representing the concepts of ‘TNB’ (the population of interest) and ‘substance use and misuse’ (outcome) will be employed. Identified records will be initially screened via a review of titles and abstracts. Full text of the remaining records will be reviewed corresponding to the inclusion and exclusion criteria. Extracted data will be synthesised in table and narrative format. A meta-analysis will be considered contingent on the existence of sufficient data. Methodological quality and risk of bias of studies will be assessed.Ethics and dissemination This review does not require approval from the Institutional Review Board as it involves no interactions with human subjects. We will disseminate our findings via peer-reviewed manuscripts and academic conference presentations.PROSPERO registration number CRD42023394985.https://bmjopen.bmj.com/content/13/8/e073877.full |
| spellingShingle | Darren L Whitfield Tural Mammadli Gail Betz Linda-Jeanne M Mack Protocol for a systematic review of substance use and misuse prevalence and associated factors among transgender and non-binary youth living in the USA BMJ Open |
| title | Protocol for a systematic review of substance use and misuse prevalence and associated factors among transgender and non-binary youth living in the USA |
| title_full | Protocol for a systematic review of substance use and misuse prevalence and associated factors among transgender and non-binary youth living in the USA |
| title_fullStr | Protocol for a systematic review of substance use and misuse prevalence and associated factors among transgender and non-binary youth living in the USA |
| title_full_unstemmed | Protocol for a systematic review of substance use and misuse prevalence and associated factors among transgender and non-binary youth living in the USA |
| title_short | Protocol for a systematic review of substance use and misuse prevalence and associated factors among transgender and non-binary youth living in the USA |
| title_sort | protocol for a systematic review of substance use and misuse prevalence and associated factors among transgender and non binary youth living in the usa |
| url | https://bmjopen.bmj.com/content/13/8/e073877.full |
| work_keys_str_mv | AT darrenlwhitfield protocolforasystematicreviewofsubstanceuseandmisuseprevalenceandassociatedfactorsamongtransgenderandnonbinaryyouthlivingintheusa AT turalmammadli protocolforasystematicreviewofsubstanceuseandmisuseprevalenceandassociatedfactorsamongtransgenderandnonbinaryyouthlivingintheusa AT gailbetz protocolforasystematicreviewofsubstanceuseandmisuseprevalenceandassociatedfactorsamongtransgenderandnonbinaryyouthlivingintheusa AT lindajeannemmack protocolforasystematicreviewofsubstanceuseandmisuseprevalenceandassociatedfactorsamongtransgenderandnonbinaryyouthlivingintheusa |