Metastatic squamous cell carcinoma arising from a retrorectal cystic hamartoma (tailgut cyst)
We report a case of a metastatic squamous cell carcinoma arising from a retrorectal cystic hamartoma (RCH). The RCH was first diagnosed at Singapore General Hospital (SGH) on magnetic resonance imaging (MRI) scan, and subsequently underwent malignant transformation and metastasized years later. Mali...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2020-06-01
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| Series: | Human Pathology: Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214330020300316 |
| _version_ | 1818510923360370688 |
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| author | Sei Kiat Tay Rafay Azhar |
| author_facet | Sei Kiat Tay Rafay Azhar |
| author_sort | Sei Kiat Tay |
| collection | DOAJ |
| description | We report a case of a metastatic squamous cell carcinoma arising from a retrorectal cystic hamartoma (RCH). The RCH was first diagnosed at Singapore General Hospital (SGH) on magnetic resonance imaging (MRI) scan, and subsequently underwent malignant transformation and metastasized years later. Malignant transformation of RCHs is an exceedingly rare event and usually manifests as an adenocarcinoma or a well differentiated neuroendocrine tumour. There have only been two previously reported cases of squamous cell carcinoma and neither of them lead to metastatic disease. This is the first reported case of a metastatic tumour arising from a RCH. |
| first_indexed | 2024-12-10T23:26:38Z |
| format | Article |
| id | doaj.art-d78606741b974d369830626b87ad0b32 |
| institution | Directory Open Access Journal |
| issn | 2214-3300 |
| language | English |
| last_indexed | 2024-12-10T23:26:38Z |
| publishDate | 2020-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Human Pathology: Case Reports |
| spelling | doaj.art-d78606741b974d369830626b87ad0b322022-12-22T01:29:34ZengElsevierHuman Pathology: Case Reports2214-33002020-06-0120200382Metastatic squamous cell carcinoma arising from a retrorectal cystic hamartoma (tailgut cyst)Sei Kiat Tay0Rafay Azhar1Corresponding author.; Department of Anatomical Pathology, Division of Pathology, Singapore General Hospital, SingaporeDepartment of Anatomical Pathology, Division of Pathology, Singapore General Hospital, SingaporeWe report a case of a metastatic squamous cell carcinoma arising from a retrorectal cystic hamartoma (RCH). The RCH was first diagnosed at Singapore General Hospital (SGH) on magnetic resonance imaging (MRI) scan, and subsequently underwent malignant transformation and metastasized years later. Malignant transformation of RCHs is an exceedingly rare event and usually manifests as an adenocarcinoma or a well differentiated neuroendocrine tumour. There have only been two previously reported cases of squamous cell carcinoma and neither of them lead to metastatic disease. This is the first reported case of a metastatic tumour arising from a RCH.http://www.sciencedirect.com/science/article/pii/S2214330020300316RetrorectalTailgutHamartomaRCHCystCystic |
| spellingShingle | Sei Kiat Tay Rafay Azhar Metastatic squamous cell carcinoma arising from a retrorectal cystic hamartoma (tailgut cyst) Human Pathology: Case Reports Retrorectal Tailgut Hamartoma RCH Cyst Cystic |
| title | Metastatic squamous cell carcinoma arising from a retrorectal cystic hamartoma (tailgut cyst) |
| title_full | Metastatic squamous cell carcinoma arising from a retrorectal cystic hamartoma (tailgut cyst) |
| title_fullStr | Metastatic squamous cell carcinoma arising from a retrorectal cystic hamartoma (tailgut cyst) |
| title_full_unstemmed | Metastatic squamous cell carcinoma arising from a retrorectal cystic hamartoma (tailgut cyst) |
| title_short | Metastatic squamous cell carcinoma arising from a retrorectal cystic hamartoma (tailgut cyst) |
| title_sort | metastatic squamous cell carcinoma arising from a retrorectal cystic hamartoma tailgut cyst |
| topic | Retrorectal Tailgut Hamartoma RCH Cyst Cystic |
| url | http://www.sciencedirect.com/science/article/pii/S2214330020300316 |
| work_keys_str_mv | AT seikiattay metastaticsquamouscellcarcinomaarisingfromaretrorectalcystichamartomatailgutcyst AT rafayazhar metastaticsquamouscellcarcinomaarisingfromaretrorectalcystichamartomatailgutcyst |