Differential diagnosis of idiopathic hypoparathyroidism: a case series
Idiopathic hypoparathyroidism is a rare endocrine disease diagnosed when all possible causes of hypoparathyroidism are excluded.Data on the prevalence of idiopathic hypoparathyroidism is limited, there are several local studies in some countries. The variety and non-specificity of the hypoparathyroi...
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| Format: | Article |
| Language: | English |
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Endocrinology Research Centre
2021-10-01
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| Series: | Ожирение и метаболизм |
| Subjects: | |
| Online Access: | https://www.omet-endojournals.ru/jour/article/view/12726 |
| _version_ | 1827121736152252416 |
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| author | T. M. Afonasyeva E. V. Kovaleva A. K. Eremkina N. G. Mokrysheva |
| author_facet | T. M. Afonasyeva E. V. Kovaleva A. K. Eremkina N. G. Mokrysheva |
| author_sort | T. M. Afonasyeva |
| collection | DOAJ |
| description | Idiopathic hypoparathyroidism is a rare endocrine disease diagnosed when all possible causes of hypoparathyroidism are excluded.Data on the prevalence of idiopathic hypoparathyroidism is limited, there are several local studies in some countries. The variety and non-specificity of the hypoparathyroidism symptoms, similarity to other diseases (eg. epilepsy), causes the misdiagnosis and delay in pathogenetic therapy.Idiopathic hypoparathyroidism is rare. Therefore, the absence of neck surgery in the anamnesis practically excludes hypoparathyroidism from the diagnostic search. Moreover, it is necessary to rule out all known causes of decreased PTH hypoparathyroidism to determine the form of non-surgical hypoparathyroidism.We present a case series of idiopathic hypoparathyroidism, which demonstrates the difficulty in diagnosis, and the clinical features of the disease. The article covers also the problem of modern diagnostic approaches including the determination of the interferon-omega for patients with suspected autoimmune polyglandular syndrome type 1 as the most common cause of nonsurgical hypoparathyroidism. |
| first_indexed | 2024-03-08T09:12:39Z |
| format | Article |
| id | doaj.art-d7892dde7a0a4ab88d7a4c36c8cff8f1 |
| institution | Directory Open Access Journal |
| issn | 2071-8713 2306-5524 |
| language | English |
| last_indexed | 2025-03-20T13:57:52Z |
| publishDate | 2021-10-01 |
| publisher | Endocrinology Research Centre |
| record_format | Article |
| series | Ожирение и метаболизм |
| spelling | doaj.art-d7892dde7a0a4ab88d7a4c36c8cff8f12024-09-11T16:17:52ZengEndocrinology Research CentreОжирение и метаболизм2071-87132306-55242021-10-0118327628110.14341/omet1272610882Differential diagnosis of idiopathic hypoparathyroidism: a case seriesT. M. Afonasyeva0E. V. Kovaleva1A. K. Eremkina2N. G. Mokrysheva3Endocrinology Research CentreEndocrinology Research CentreEndocrinology Research CentreEndocrinology Research CentreIdiopathic hypoparathyroidism is a rare endocrine disease diagnosed when all possible causes of hypoparathyroidism are excluded.Data on the prevalence of idiopathic hypoparathyroidism is limited, there are several local studies in some countries. The variety and non-specificity of the hypoparathyroidism symptoms, similarity to other diseases (eg. epilepsy), causes the misdiagnosis and delay in pathogenetic therapy.Idiopathic hypoparathyroidism is rare. Therefore, the absence of neck surgery in the anamnesis practically excludes hypoparathyroidism from the diagnostic search. Moreover, it is necessary to rule out all known causes of decreased PTH hypoparathyroidism to determine the form of non-surgical hypoparathyroidism.We present a case series of idiopathic hypoparathyroidism, which demonstrates the difficulty in diagnosis, and the clinical features of the disease. The article covers also the problem of modern diagnostic approaches including the determination of the interferon-omega for patients with suspected autoimmune polyglandular syndrome type 1 as the most common cause of nonsurgical hypoparathyroidism.https://www.omet-endojournals.ru/jour/article/view/12726idiopathic hypoparathyroidismautoimmune polyglandular syndrome type ipostsurgical hypoparathyroidismdifferential diagnostics |
| spellingShingle | T. M. Afonasyeva E. V. Kovaleva A. K. Eremkina N. G. Mokrysheva Differential diagnosis of idiopathic hypoparathyroidism: a case series Ожирение и метаболизм idiopathic hypoparathyroidism autoimmune polyglandular syndrome type i postsurgical hypoparathyroidism differential diagnostics |
| title | Differential diagnosis of idiopathic hypoparathyroidism: a case series |
| title_full | Differential diagnosis of idiopathic hypoparathyroidism: a case series |
| title_fullStr | Differential diagnosis of idiopathic hypoparathyroidism: a case series |
| title_full_unstemmed | Differential diagnosis of idiopathic hypoparathyroidism: a case series |
| title_short | Differential diagnosis of idiopathic hypoparathyroidism: a case series |
| title_sort | differential diagnosis of idiopathic hypoparathyroidism a case series |
| topic | idiopathic hypoparathyroidism autoimmune polyglandular syndrome type i postsurgical hypoparathyroidism differential diagnostics |
| url | https://www.omet-endojournals.ru/jour/article/view/12726 |
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