Risk factors for acute kidney injury in COVID-19 patients: an updated systematic review and meta-analysis
Objectives Acute kidney injury (AKI) is associated with increased mortality among coronavirus disease 2019 (COVID-19) patients. This meta-analysis aimed to identify risk factors for the development of AKI in patients with COVID-19.Methods A systematic literature search was conducted in PubMed and EM...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2023-12-01
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| Series: | Renal Failure |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/0886022X.2023.2170809 |
| _version_ | 1826900401896554496 |
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| author | Jialing Zhang Qi Pang Ting Zhou Jiali Meng Xingtong Dong Zhe Wang Aihua Zhang |
| author_facet | Jialing Zhang Qi Pang Ting Zhou Jiali Meng Xingtong Dong Zhe Wang Aihua Zhang |
| author_sort | Jialing Zhang |
| collection | DOAJ |
| description | Objectives Acute kidney injury (AKI) is associated with increased mortality among coronavirus disease 2019 (COVID-19) patients. This meta-analysis aimed to identify risk factors for the development of AKI in patients with COVID-19.Methods A systematic literature search was conducted in PubMed and EMBASE from 1 December 2019 to 1 January 2023. Due to significant study heterogeneity, meta-analyses were conducted using random-effects models. Meta-regression and sensitivity analysis were also performed.Results A total of 153,600 COVID-19 patients from 39 studies were included, and 28,003 patients developed AKI. By meta-analysis, we discovered that age, male sex, obesity, black race, invasive ventilation, and the use of diuretics, steroids and vasopressors, in addition to comorbidities such as hypertension, congestive heart failure, chronic kidney disease, acute respiratory distress syndrome, and diabetes, were significant risk factors for COVID-19-associated AKI.Conclusions Early detection of these risk factors is essential to reduce the incidence of AKI and improve the prognosis of COVID-19 patients. |
| first_indexed | 2024-03-11T18:00:29Z |
| format | Article |
| id | doaj.art-d78f300090984dc9bc0bb6ae1cd3ccc7 |
| institution | Directory Open Access Journal |
| issn | 0886-022X 1525-6049 |
| language | English |
| last_indexed | 2025-02-17T07:07:07Z |
| publishDate | 2023-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Renal Failure |
| spelling | doaj.art-d78f300090984dc9bc0bb6ae1cd3ccc72025-01-06T03:21:20ZengTaylor & Francis GroupRenal Failure0886-022X1525-60492023-12-0145110.1080/0886022X.2023.2170809Risk factors for acute kidney injury in COVID-19 patients: an updated systematic review and meta-analysisJialing Zhang0Qi Pang1Ting Zhou2Jiali Meng3Xingtong Dong4Zhe Wang5Aihua Zhang6Department of Nephrology, Xuanwu Hospital, Capital Medical University, Beijing, ChinaDepartment of Nephrology, Xuanwu Hospital, Capital Medical University, Beijing, ChinaDepartment of Nephrology, Xuanwu Hospital, Capital Medical University, Beijing, ChinaDepartment of Nephrology, Xuanwu Hospital, Capital Medical University, Beijing, ChinaDepartment of Nephrology, Xuanwu Hospital, Capital Medical University, Beijing, ChinaAdvanced Innovation Center for Human Brain Protection, The National Clinical Research Center for Geriatric Disease, Xuanwu Hospital, Capital Medical University, Beijing, ChinaDepartment of Nephrology, Xuanwu Hospital, Capital Medical University, Beijing, ChinaObjectives Acute kidney injury (AKI) is associated with increased mortality among coronavirus disease 2019 (COVID-19) patients. This meta-analysis aimed to identify risk factors for the development of AKI in patients with COVID-19.Methods A systematic literature search was conducted in PubMed and EMBASE from 1 December 2019 to 1 January 2023. Due to significant study heterogeneity, meta-analyses were conducted using random-effects models. Meta-regression and sensitivity analysis were also performed.Results A total of 153,600 COVID-19 patients from 39 studies were included, and 28,003 patients developed AKI. By meta-analysis, we discovered that age, male sex, obesity, black race, invasive ventilation, and the use of diuretics, steroids and vasopressors, in addition to comorbidities such as hypertension, congestive heart failure, chronic kidney disease, acute respiratory distress syndrome, and diabetes, were significant risk factors for COVID-19-associated AKI.Conclusions Early detection of these risk factors is essential to reduce the incidence of AKI and improve the prognosis of COVID-19 patients.https://www.tandfonline.com/doi/10.1080/0886022X.2023.2170809Acute kidney injuryCOVID-19systematic reviewmeta-analysis |
| spellingShingle | Jialing Zhang Qi Pang Ting Zhou Jiali Meng Xingtong Dong Zhe Wang Aihua Zhang Risk factors for acute kidney injury in COVID-19 patients: an updated systematic review and meta-analysis Renal Failure Acute kidney injury COVID-19 systematic review meta-analysis |
| title | Risk factors for acute kidney injury in COVID-19 patients: an updated systematic review and meta-analysis |
| title_full | Risk factors for acute kidney injury in COVID-19 patients: an updated systematic review and meta-analysis |
| title_fullStr | Risk factors for acute kidney injury in COVID-19 patients: an updated systematic review and meta-analysis |
| title_full_unstemmed | Risk factors for acute kidney injury in COVID-19 patients: an updated systematic review and meta-analysis |
| title_short | Risk factors for acute kidney injury in COVID-19 patients: an updated systematic review and meta-analysis |
| title_sort | risk factors for acute kidney injury in covid 19 patients an updated systematic review and meta analysis |
| topic | Acute kidney injury COVID-19 systematic review meta-analysis |
| url | https://www.tandfonline.com/doi/10.1080/0886022X.2023.2170809 |
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