Electrochemical Non-Enzymatic Detection of Glucose Based on 3D Electroformed Copper on Ni Foam Nanostructures
Despite the fact that the electrochemical biosensors based on glucose oxidase represent the golden standard for the management of diabetes, the elaboration of nonenzymatic sensors became extensively studied as an out-of-the-box concept that aims to simplify the existing approach. An important point...
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| Language: | English |
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MDPI AG
2020-06-01
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| Series: | Materials |
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| Online Access: | https://www.mdpi.com/1996-1944/13/12/2752 |
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| author | Gheorghe Melinte Andreea Cernat Aurora Petica Oana Lazar Marius Enachescu Liana Anicai Cecilia Cristea |
| author_facet | Gheorghe Melinte Andreea Cernat Aurora Petica Oana Lazar Marius Enachescu Liana Anicai Cecilia Cristea |
| author_sort | Gheorghe Melinte |
| collection | DOAJ |
| description | Despite the fact that the electrochemical biosensors based on glucose oxidase represent the golden standard for the management of diabetes, the elaboration of nonenzymatic sensors became extensively studied as an out-of-the-box concept that aims to simplify the existing approach. An important point of view is represented by the low price of the sensing device that has positive effects for both end-users and healthcare systems. The enzyme-free sensors based on low-cost materials such as transition metals have similar analytical properties to the commercial ones while eliminating the issues associated with the presence of the enzyme, such as the stability issues and limited shelf-life. The development of nanoporous nanomaterials for biomedical applications and electrocatalysis was referred to as an alternative to the conventional methods due to their enlarged area, electrical properties, ease of functionalization and not least to their low cost. Herein, we report the development of an electrochemical nonenzymatic sensor for glucose based on 3D copper nanostructures with Ni foams as promotor of the enhanced nanoporous morphology. The sensors were successfully tested in the presence of the designated target, even in the presence of common interference agents found in biological samples. |
| first_indexed | 2024-03-10T19:06:32Z |
| format | Article |
| id | doaj.art-d791248cecd64af5989e17e746d13fb6 |
| institution | Directory Open Access Journal |
| issn | 1996-1944 |
| language | English |
| last_indexed | 2024-03-10T19:06:32Z |
| publishDate | 2020-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Materials |
| spelling | doaj.art-d791248cecd64af5989e17e746d13fb62023-11-20T04:09:25ZengMDPI AGMaterials1996-19442020-06-011312275210.3390/ma13122752Electrochemical Non-Enzymatic Detection of Glucose Based on 3D Electroformed Copper on Ni Foam NanostructuresGheorghe Melinte0Andreea Cernat1Aurora Petica2Oana Lazar3Marius Enachescu4Liana Anicai5Cecilia Cristea6Analytical Chemistry Department, Faculty of Pharmacy, Iuliu Haţieganu University of Medicine and Pharmacy, 4 Louis Pasteur St., 400349 Cluj-Napoca, RomaniaAnalytical Chemistry Department, Faculty of Pharmacy, Iuliu Haţieganu University of Medicine and Pharmacy, 4 Louis Pasteur St., 400349 Cluj-Napoca, RomaniaCenter for Surface Science and Nanotechnology, University Polytechnica of Bucharest, Splaiul Independentei 313, 060042 Bucharest, RomaniaCenter for Surface Science and Nanotechnology, University Polytechnica of Bucharest, Splaiul Independentei 313, 060042 Bucharest, RomaniaCenter for Surface Science and Nanotechnology, University Polytechnica of Bucharest, Splaiul Independentei 313, 060042 Bucharest, RomaniaCenter for Surface Science and Nanotechnology, University Polytechnica of Bucharest, Splaiul Independentei 313, 060042 Bucharest, RomaniaAnalytical Chemistry Department, Faculty of Pharmacy, Iuliu Haţieganu University of Medicine and Pharmacy, 4 Louis Pasteur St., 400349 Cluj-Napoca, RomaniaDespite the fact that the electrochemical biosensors based on glucose oxidase represent the golden standard for the management of diabetes, the elaboration of nonenzymatic sensors became extensively studied as an out-of-the-box concept that aims to simplify the existing approach. An important point of view is represented by the low price of the sensing device that has positive effects for both end-users and healthcare systems. The enzyme-free sensors based on low-cost materials such as transition metals have similar analytical properties to the commercial ones while eliminating the issues associated with the presence of the enzyme, such as the stability issues and limited shelf-life. The development of nanoporous nanomaterials for biomedical applications and electrocatalysis was referred to as an alternative to the conventional methods due to their enlarged area, electrical properties, ease of functionalization and not least to their low cost. Herein, we report the development of an electrochemical nonenzymatic sensor for glucose based on 3D copper nanostructures with Ni foams as promotor of the enhanced nanoporous morphology. The sensors were successfully tested in the presence of the designated target, even in the presence of common interference agents found in biological samples.https://www.mdpi.com/1996-1944/13/12/2752glucosemodified electrodesnon-enzymatic detection3D electroformed Cuelectrochemical detection |
| spellingShingle | Gheorghe Melinte Andreea Cernat Aurora Petica Oana Lazar Marius Enachescu Liana Anicai Cecilia Cristea Electrochemical Non-Enzymatic Detection of Glucose Based on 3D Electroformed Copper on Ni Foam Nanostructures Materials glucose modified electrodes non-enzymatic detection 3D electroformed Cu electrochemical detection |
| title | Electrochemical Non-Enzymatic Detection of Glucose Based on 3D Electroformed Copper on Ni Foam Nanostructures |
| title_full | Electrochemical Non-Enzymatic Detection of Glucose Based on 3D Electroformed Copper on Ni Foam Nanostructures |
| title_fullStr | Electrochemical Non-Enzymatic Detection of Glucose Based on 3D Electroformed Copper on Ni Foam Nanostructures |
| title_full_unstemmed | Electrochemical Non-Enzymatic Detection of Glucose Based on 3D Electroformed Copper on Ni Foam Nanostructures |
| title_short | Electrochemical Non-Enzymatic Detection of Glucose Based on 3D Electroformed Copper on Ni Foam Nanostructures |
| title_sort | electrochemical non enzymatic detection of glucose based on 3d electroformed copper on ni foam nanostructures |
| topic | glucose modified electrodes non-enzymatic detection 3D electroformed Cu electrochemical detection |
| url | https://www.mdpi.com/1996-1944/13/12/2752 |
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