Highly Efficient Synthesis of Substituted 3,4-Dihydropyrimidin-2-(1<i>H</i>)-ones (DHPMs) Catalyzed by Hf(OTf)<sub>4</sub>: Mechanistic Insights into Reaction Pathways under Metal Lewis Acid Catalysis and Solvent-Free Conditions

Highly Efficient Synthesis of Substituted 3,4-Dihydropyrimidin-2-(1<i>H</i>)-ones (DHPMs) Catalyzed by Hf(OTf)<sub>4</sub>: Mechanistic Insights into Reaction Pathways under Metal Lewis Acid Catalysis and Solvent-Free Conditions

In our studies on the catalytic activity of Group IVB transition metal Lewis acids, Hf(OTf)<sub>4</sub> was identified as a highly potent catalyst for „one-pot, three-component„ Biginelli reaction. More importantly, it was found that solvent-free conditions, in contra...

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Bibliographic Details
Main Authors:	Rui Kong, Shuai-Bo Han, Jing-Ying Wei, Xiao-Chong Peng, Zhen-Biao Xie, Shan-Shan Gong, Qi Sun
Format:	Article
Language:	English
Published:	MDPI AG 2019-01-01
Series:	Molecules
Subjects:	hafnium triflate 3,4-dihydropyrimidin-2-(1<i>H</i>)-ones solvent-free Biginelli reaction mechanism
Online Access:	https://www.mdpi.com/1420-3049/24/2/364

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