Comparative Genomic and Physiological Analysis against <i>Clostridium scindens</i> Reveals <i>Eubacterium</i> sp. c-25 as an Atypical Deoxycholic Acid Producer of the Human Gut Microbiota

Comparative Genomic and Physiological Analysis against <i>Clostridium scindens</i> Reveals <i>Eubacterium</i> sp. c-25 as an Atypical Deoxycholic Acid Producer of the Human Gut Microbiota

The human gut houses bile acid 7α-dehydroxylating bacteria that produce secondary bile acids such as deoxycholic acid (DCA) from host-derived bile acids through enzymes encoded by the <i>bai</i> operon. While recent metagenomic studies suggest that these bacteria are highly diverse and a...

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Bibliographic Details
Main Authors: Isaiah Song, Yasuhiro Gotoh, Yoshitoshi Ogura, Tetsuya Hayashi, Satoru Fukiya, Atsushi Yokota
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Microorganisms
Subjects:
secondary bile acid
deoxycholic acid
<i>bai</i> operon
gut microbiome
<i>Clostridium scindens</i>
Online Access:https://www.mdpi.com/2076-2607/9/11/2254

Internet

https://www.mdpi.com/2076-2607/9/11/2254

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