Antitumor activity of acidic ingredient from Solidago canadensis L(加拿大一枝黄花中酸性成分抗肿瘤活性初探)
探讨加拿大一枝黄花（Solidago canadensis L.）花序乙酸乙酯提取物中酸性成分体外及体内抗肿瘤活性.采用MTT法跟踪提取物细胞毒活性；用S180和EAC昆明小鼠模型进行提取物的体内抗肿瘤活性评价.结果表明，加拿大一枝黄花花序的酸性成分具有显著抑制多株人肿瘤细胞株生长的作用，并呈明显的量效关系.乙酸乙酯提取物中的酸性成分对小鼠移植性肿瘤S180和EAC的生长也有显著的抑制作用，并和剂量正相关，高剂量组对小鼠移植性肿瘤S180和EAC的抑制率分别为52.06%，32.90%.显示了加拿大一枝黄花具有较强的体内和体外抗肿瘤作用....
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | zho |
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Zhejiang University Press
2007-07-01
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| Series: | Zhejiang Daxue xuebao. Lixue ban |
| Subjects: | |
| Online Access: | https://doi.org/zjup/1008-9497.2007.34.4.451-454 |
| _version_ | 1797236261854904320 |
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| author | ZHUHong-ke(朱宏科) LIUXiao-yue(刘晓月) WUShi-hua(吴世华) LIUFei-yan(刘非燕) CHENGYun-long(陈云龙) WUPing(吴平) |
| author_facet | ZHUHong-ke(朱宏科) LIUXiao-yue(刘晓月) WUShi-hua(吴世华) LIUFei-yan(刘非燕) CHENGYun-long(陈云龙) WUPing(吴平) |
| author_sort | ZHUHong-ke(朱宏科) |
| collection | DOAJ |
| description | 探讨加拿大一枝黄花（Solidago canadensis L.）花序乙酸乙酯提取物中酸性成分体外及体内抗肿瘤活性.采用MTT法跟踪提取物细胞毒活性；用S180和EAC昆明小鼠模型进行提取物的体内抗肿瘤活性评价.结果表明，加拿大一枝黄花花序的酸性成分具有显著抑制多株人肿瘤细胞株生长的作用，并呈明显的量效关系.乙酸乙酯提取物中的酸性成分对小鼠移植性肿瘤S180和EAC的生长也有显著的抑制作用，并和剂量正相关，高剂量组对小鼠移植性肿瘤S180和EAC的抑制率分别为52.06%，32.90%.显示了加拿大一枝黄花具有较强的体内和体外抗肿瘤作用. |
| first_indexed | 2024-04-24T17:01:03Z |
| format | Article |
| id | doaj.art-d7a05dc0fa504988b23af560b5c23102 |
| institution | Directory Open Access Journal |
| issn | 1008-9497 |
| language | zho |
| last_indexed | 2024-04-24T17:01:03Z |
| publishDate | 2007-07-01 |
| publisher | Zhejiang University Press |
| record_format | Article |
| series | Zhejiang Daxue xuebao. Lixue ban |
| spelling | doaj.art-d7a05dc0fa504988b23af560b5c231022024-03-29T01:58:24ZzhoZhejiang University PressZhejiang Daxue xuebao. Lixue ban1008-94972007-07-01344451454zjup/1008-9497.2007.34.4.451-454Antitumor activity of acidic ingredient from Solidago canadensis L(加拿大一枝黄花中酸性成分抗肿瘤活性初探)ZHUHong-ke(朱宏科)0LIUXiao-yue(刘晓月)1WUShi-hua(吴世华)2LIUFei-yan(刘非燕)3CHENGYun-long(陈云龙)4WUPing(吴平)5College of Life Sciences, Zhejiang University, Hangzhou 310058, China(浙江大学生命科学学院，浙江 杭州 310058)College of Life Sciences, Zhejiang University, Hangzhou 310058, China(浙江大学生命科学学院，浙江 杭州 310058)College of Life Sciences, Zhejiang University, Hangzhou 310058, China(浙江大学生命科学学院，浙江 杭州 310058)College of Life Sciences, Zhejiang University, Hangzhou 310058, China(浙江大学生命科学学院，浙江 杭州 310058)College of Life Sciences, Zhejiang University, Hangzhou 310058, China(浙江大学生命科学学院，浙江 杭州 310058)College of Life Sciences, Zhejiang University, Hangzhou 310058, China(浙江大学生命科学学院，浙江 杭州 310058)探讨加拿大一枝黄花（Solidago canadensis L.）花序乙酸乙酯提取物中酸性成分体外及体内抗肿瘤活性.采用MTT法跟踪提取物细胞毒活性；用S180和EAC昆明小鼠模型进行提取物的体内抗肿瘤活性评价.结果表明，加拿大一枝黄花花序的酸性成分具有显著抑制多株人肿瘤细胞株生长的作用，并呈明显的量效关系.乙酸乙酯提取物中的酸性成分对小鼠移植性肿瘤S180和EAC的生长也有显著的抑制作用，并和剂量正相关，高剂量组对小鼠移植性肿瘤S180和EAC的抑制率分别为52.06%，32.90%.显示了加拿大一枝黄花具有较强的体内和体外抗肿瘤作用.https://doi.org/zjup/1008-9497.2007.34.4.451-454加拿大一枝黄花抗肿瘤 |
| spellingShingle | ZHUHong-ke(朱宏科) LIUXiao-yue(刘晓月) WUShi-hua(吴世华) LIUFei-yan(刘非燕) CHENGYun-long(陈云龙) WUPing(吴平) Antitumor activity of acidic ingredient from Solidago canadensis L(加拿大一枝黄花中酸性成分抗肿瘤活性初探) Zhejiang Daxue xuebao. Lixue ban 加拿大一枝黄花 抗肿瘤 |
| title | Antitumor activity of acidic ingredient from Solidago canadensis L(加拿大一枝黄花中酸性成分抗肿瘤活性初探) |
| title_full | Antitumor activity of acidic ingredient from Solidago canadensis L(加拿大一枝黄花中酸性成分抗肿瘤活性初探) |
| title_fullStr | Antitumor activity of acidic ingredient from Solidago canadensis L(加拿大一枝黄花中酸性成分抗肿瘤活性初探) |
| title_full_unstemmed | Antitumor activity of acidic ingredient from Solidago canadensis L(加拿大一枝黄花中酸性成分抗肿瘤活性初探) |
| title_short | Antitumor activity of acidic ingredient from Solidago canadensis L(加拿大一枝黄花中酸性成分抗肿瘤活性初探) |
| title_sort | antitumor activity of acidic ingredient from solidago canadensis l 加拿大一枝黄花中酸性成分抗肿瘤活性初探 |
| topic | 加拿大一枝黄花 抗肿瘤 |
| url | https://doi.org/zjup/1008-9497.2007.34.4.451-454 |
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