Doravirine-associated resistance mutations in antiretroviral therapy naïve and experienced adults with HIV-1 subtype C infection in Botswana

Doravirine-associated resistance mutations in antiretroviral therapy naïve and experienced adults with HIV-1 subtype C infection in Botswana

ABSTRACT: Objectives: There are limited data on the prevalence of doravirine (DOR)-associated drug resistance mutations in people with HIV (PWH) in Botswana. This cross-sectional, retrospective study aimed to explore the prevalence of DOR-associated resistance mutations among ART-naïve and -experie...

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Main Authors: Ontlametse T. Bareng, Sekgabo Seselamarumo, Kaelo K. Seatla, Wonderful T. Choga, Blessing Bakae, Dorcas Maruapula, Nametso Kelentse, Natasha O. Moraka, Baitshepi Mokaleng, Patrick T. Mokgethi, Tsotlhe R. Ditlhako, Molly Pretorius-Holme, Mpaphi B. Mbulawa, Refeletswe Lebelonyane, Ebi Celestin Bile, Tendani Gaolathe, Roger Shapiro, Joseph M. Makhema, Shahin Lockman, Max Essex, Vlad Novitsky, Sununguko W. Mpoloka, Sikhulile Moyo, Simani Gaseitsiwe
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
HIV-1C
Drug resistance mutations
Antiretroviral (ART) experienced
Antiretroviral (ART) naive
Doravirine
Botswana
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716522001989

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