FOXP3<sup>+ </sup>T<sub>regs </sub>and B7-H1<sup>+</sup>/PD-1<sup>+ </sup>T lymphocytes co-infiltrate the tumor tissues of high-risk breast cancer patients: Implication for immunotherapy

FOXP3<sup>+ </sup>T<sub>regs </sub>and B7-H1<sup>+</sup>/PD-1<sup>+ </sup>T lymphocytes co-infiltrate the tumor tissues of high-risk breast cancer patients: Implication for immunotherapy

<p>Abstract</p> <p>Background</p> <p>Recent studies have demonstrated a direct involvement of B7-H1, PD-1 and FOXP3 molecules in the immune escape of cancer. B7-H1 is an inhibitory molecule that binds to PD-1 on T lymphocytes, while FOXP3 is a marker for regulatory T ce...

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Bibliographic Details
Main Authors:	Al-Tweigeri Taher, Elkum Naser, Tulbah Asma, Barhoush Eman, Ghebeh Hazem, Dermime Said
Format:	Article
Language:	English
Published:	BMC 2008-02-01
Series:	BMC Cancer
Online Access:	http://www.biomedcentral.com/1471-2407/8/57

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