Bilateral Basal Cell Adenocarcinoma of the Parotid Gland: In a Recipient of Kidney Transplant
We report a rare case of bilateral basal cell adenocarcinoma (BcAC) of the parotid gland in a male patient 30 years after kidney transplantation and continuous administration of immunosuppressive therapy. BcAC is a salivary gland malignancy first recognized as a distinct neoplastic entity in WHO cla...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2010-01-01
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| Series: | Clinical Medicine Insights: Pathology |
| Online Access: | https://doi.org/10.4137/CPath.S3303 |
| _version_ | 1819153644443926528 |
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| author | Mari Markkanen-Leppänen Antti A. Mäkitie Fabricio Passador-Santos Ilmo Leivo Jaana Hagström |
| author_facet | Mari Markkanen-Leppänen Antti A. Mäkitie Fabricio Passador-Santos Ilmo Leivo Jaana Hagström |
| author_sort | Mari Markkanen-Leppänen |
| collection | DOAJ |
| description | We report a rare case of bilateral basal cell adenocarcinoma (BcAC) of the parotid gland in a male patient 30 years after kidney transplantation and continuous administration of immunosuppressive therapy. BcAC is a salivary gland malignancy first recognized as a distinct neoplastic entity in WHO classification of salivary gland tumours in 1991. Over 90% of BcACs are detected in the parotid gland. The most important differential diagnosis is basal cell adenoma. Infiltrative growth is the distinguishing feature of BcAC. Administration of immunosuppressive medication to this patient for three decades may have contributed to development of this rare neoplasia. To our knowledge, similar cases of BcAC have not been reported previously. |
| first_indexed | 2024-12-22T15:08:28Z |
| format | Article |
| id | doaj.art-d7a53bf82991492f8006825445c6f21a |
| institution | Directory Open Access Journal |
| issn | 1179-5557 |
| language | English |
| last_indexed | 2024-12-22T15:08:28Z |
| publishDate | 2010-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Clinical Medicine Insights: Pathology |
| spelling | doaj.art-d7a53bf82991492f8006825445c6f21a2022-12-21T18:21:55ZengSAGE PublishingClinical Medicine Insights: Pathology1179-55572010-01-01310.4137/CPath.S3303Bilateral Basal Cell Adenocarcinoma of the Parotid Gland: In a Recipient of Kidney TransplantMari Markkanen-Leppänen0Antti A. Mäkitie1Fabricio Passador-Santos2Ilmo Leivo3Jaana Hagström4Department of Otolaryngology and Head and Neck Surgery, Helsinki University Central Hospital, and Department of Pathology, Haartman Institute, University of Helsinki, Helsinki, Finland.Department of Otolaryngology and Head and Neck Surgery, Helsinki University Central Hospital, and Department of Pathology, Haartman Institute, University of Helsinki, Helsinki, Finland.Department of Otolaryngology and Head and Neck Surgery, Helsinki University Central Hospital, and Department of Pathology, Haartman Institute, University of Helsinki, Helsinki, Finland.Department of Otolaryngology and Head and Neck Surgery, Helsinki University Central Hospital, and Department of Pathology, Haartman Institute, University of Helsinki, Helsinki, Finland.Department of Otolaryngology and Head and Neck Surgery, Helsinki University Central Hospital, and Department of Pathology, Haartman Institute, University of Helsinki, Helsinki, Finland.We report a rare case of bilateral basal cell adenocarcinoma (BcAC) of the parotid gland in a male patient 30 years after kidney transplantation and continuous administration of immunosuppressive therapy. BcAC is a salivary gland malignancy first recognized as a distinct neoplastic entity in WHO classification of salivary gland tumours in 1991. Over 90% of BcACs are detected in the parotid gland. The most important differential diagnosis is basal cell adenoma. Infiltrative growth is the distinguishing feature of BcAC. Administration of immunosuppressive medication to this patient for three decades may have contributed to development of this rare neoplasia. To our knowledge, similar cases of BcAC have not been reported previously.https://doi.org/10.4137/CPath.S3303 |
| spellingShingle | Mari Markkanen-Leppänen Antti A. Mäkitie Fabricio Passador-Santos Ilmo Leivo Jaana Hagström Bilateral Basal Cell Adenocarcinoma of the Parotid Gland: In a Recipient of Kidney Transplant Clinical Medicine Insights: Pathology |
| title | Bilateral Basal Cell Adenocarcinoma of the Parotid Gland: In a Recipient of Kidney Transplant |
| title_full | Bilateral Basal Cell Adenocarcinoma of the Parotid Gland: In a Recipient of Kidney Transplant |
| title_fullStr | Bilateral Basal Cell Adenocarcinoma of the Parotid Gland: In a Recipient of Kidney Transplant |
| title_full_unstemmed | Bilateral Basal Cell Adenocarcinoma of the Parotid Gland: In a Recipient of Kidney Transplant |
| title_short | Bilateral Basal Cell Adenocarcinoma of the Parotid Gland: In a Recipient of Kidney Transplant |
| title_sort | bilateral basal cell adenocarcinoma of the parotid gland in a recipient of kidney transplant |
| url | https://doi.org/10.4137/CPath.S3303 |
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