Viruses and thrombocytopenia
Thrombocytopenia, characterized by a decrease in platelet count, is a multifaceted clinical manifestation that can arise from various underlying causes. This review delves into the intriguing nexus between viruses and thrombocytopenia, shedding light on intricate pathophysiological mechanisms and hi...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-03-01
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| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024038751 |
| _version_ | 1797224229037408256 |
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| author | Reyhaneh Rasizadeh Fatemeh Ebrahimi Atefeh Zamani Kermanshahi Amin Daei Sorkhabi Aila Sarkesh Javid Sadri Nahand Hossein Bannazadeh Baghi |
| author_facet | Reyhaneh Rasizadeh Fatemeh Ebrahimi Atefeh Zamani Kermanshahi Amin Daei Sorkhabi Aila Sarkesh Javid Sadri Nahand Hossein Bannazadeh Baghi |
| author_sort | Reyhaneh Rasizadeh |
| collection | DOAJ |
| description | Thrombocytopenia, characterized by a decrease in platelet count, is a multifaceted clinical manifestation that can arise from various underlying causes. This review delves into the intriguing nexus between viruses and thrombocytopenia, shedding light on intricate pathophysiological mechanisms and highlighting the pivotal role of platelets in viral infections. The review further navigates the landscape of thrombocytopenia in relation to specific viruses, and sheds light on the diverse mechanisms through which hepatitis C virus (HCV), measles virus, parvovirus B19, and other viral agents contribute to platelet depletion. As we gain deeper insights into these interactions, we move closer to elucidating potential therapeutic avenues and preventive strategies for managing thrombocytopenia in the context of viral infections. |
| first_indexed | 2024-04-24T13:49:48Z |
| format | Article |
| id | doaj.art-d7b04286312f46b0903faff72d470482 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-04-24T13:49:48Z |
| publishDate | 2024-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-d7b04286312f46b0903faff72d4704822024-04-04T05:06:08ZengElsevierHeliyon2405-84402024-03-01106e27844Viruses and thrombocytopeniaReyhaneh Rasizadeh0Fatemeh Ebrahimi1Atefeh Zamani Kermanshahi2Amin Daei Sorkhabi3Aila Sarkesh4Javid Sadri Nahand5Hossein Bannazadeh Baghi6Immunology Research Centre, Tabriz University of Medical Sciences, Tabriz, Iran; Department of Virology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran; Department of Animal Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz, IranDepartment of Virology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Virology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, IranImmunology Research Centre, Tabriz University of Medical Sciences, Tabriz, Iran; Student Research Committee, Tabriz University of Medical Sciences, Tabriz, IranImmunology Research Centre, Tabriz University of Medical Sciences, Tabriz, Iran; Student Research Committee, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Virology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran; Infectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, IranImmunology Research Centre, Tabriz University of Medical Sciences, Tabriz, Iran; Department of Virology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran; Infectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; Corresponding author. Infectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, PO Box 5165665931, Tabriz, Iran.Thrombocytopenia, characterized by a decrease in platelet count, is a multifaceted clinical manifestation that can arise from various underlying causes. This review delves into the intriguing nexus between viruses and thrombocytopenia, shedding light on intricate pathophysiological mechanisms and highlighting the pivotal role of platelets in viral infections. The review further navigates the landscape of thrombocytopenia in relation to specific viruses, and sheds light on the diverse mechanisms through which hepatitis C virus (HCV), measles virus, parvovirus B19, and other viral agents contribute to platelet depletion. As we gain deeper insights into these interactions, we move closer to elucidating potential therapeutic avenues and preventive strategies for managing thrombocytopenia in the context of viral infections.http://www.sciencedirect.com/science/article/pii/S2405844024038751ThrombocytopeniaPlateletsCoagulationInflammationThrombosis |
| spellingShingle | Reyhaneh Rasizadeh Fatemeh Ebrahimi Atefeh Zamani Kermanshahi Amin Daei Sorkhabi Aila Sarkesh Javid Sadri Nahand Hossein Bannazadeh Baghi Viruses and thrombocytopenia Heliyon Thrombocytopenia Platelets Coagulation Inflammation Thrombosis |
| title | Viruses and thrombocytopenia |
| title_full | Viruses and thrombocytopenia |
| title_fullStr | Viruses and thrombocytopenia |
| title_full_unstemmed | Viruses and thrombocytopenia |
| title_short | Viruses and thrombocytopenia |
| title_sort | viruses and thrombocytopenia |
| topic | Thrombocytopenia Platelets Coagulation Inflammation Thrombosis |
| url | http://www.sciencedirect.com/science/article/pii/S2405844024038751 |
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