Diagnostic value of high resolution computed tomographic scan in active pulmonary tuberculosis
Background and Objective: Since accurate and quick clinical and paraclinical diagnostic methods are not available, in some cases diagnosis of active pulmonary tuberculosis occurs after considerable time from the onset of disease. This study was designed to determine the diagnostic value of High Reso...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | fas |
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Golestan University of Medical Sciences
2012-12-01
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| Series: | مجله دانشگاه علوم پزشکی گرگان |
| Subjects: | |
| Online Access: | http://goums.ac.ir/journal/browse.php?a_code=A-10-1-634&slc_lang=en&sid=1 |
| _version_ | 1811276117404811264 |
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| author | Khodabakhshi (MD) Asali A (MD) Behnampour N (MSc) Abbasi A (MD) Adel Barkhordar AR (MD) Hashemi Frad A |
| author_facet | Khodabakhshi (MD) Asali A (MD) Behnampour N (MSc) Abbasi A (MD) Adel Barkhordar AR (MD) Hashemi Frad A |
| author_sort | Khodabakhshi (MD) |
| collection | DOAJ |
| description | Background and Objective: Since accurate and quick clinical and paraclinical diagnostic methods are not available, in some cases diagnosis of active pulmonary tuberculosis occurs after considerable time from the onset of disease. This study was designed to determine the diagnostic value of High Resolution Computed Tomographic (HRCT) scan in active pulmonary tuberculosis, in Gorgan, Golestan province, North of Iran. Materials and Methods: This diagnostic screening study was carried out on 135 (79 male and 56 female) hospitalized patients suspected with active pulmonary tuberculosis, and HRCT was used in their course of treatment as recommendation of their clinician. The patients were chosen from 5th Azar hosptial during 2009-10. Also it should be mentioned that patients were selected on avaliabity bases, and they were examined by smear, and sputum culture. The patients with negative smear and culture were set up as true healthy group (64 subjects). The lung or small nuddles in HRCT was considered as proper position of lung involvument in active lung pulmonary. The HRCT findings between the case group (71 subjects) and healthy group were compared. According to HRCT findings, the sensitivity and specifity were determined for each patient. Data were analyzed using SPSS-16 and Chi-Square test. Results: In this study, sensitivity, specificity, positive predictive value and negative predictive value of HRCT in active pulmonary tuberculosis were equal to 97.2%, 71.9%, 79.3% and 95.8% respectively. Involvement of upper and middle lobe of the right lung and upper lobe of the left lung were significantly higher than the control group (P<0.05). Conclusion: This study showed that HRCT has high sensitivity and specificity in diagnosis of active pulmonary tuberculosis and can be used as a quick diagnostic way in active pulmonary tuberculosis, especially in patients with strong clinical suspicion and negative smear. |
| first_indexed | 2024-04-12T23:50:43Z |
| format | Article |
| id | doaj.art-d7b506e5be0e415282cd284b7cbe76f5 |
| institution | Directory Open Access Journal |
| issn | 1562-4765 2008-4080 |
| language | fas |
| last_indexed | 2024-04-12T23:50:43Z |
| publishDate | 2012-12-01 |
| publisher | Golestan University of Medical Sciences |
| record_format | Article |
| series | مجله دانشگاه علوم پزشکی گرگان |
| spelling | doaj.art-d7b506e5be0e415282cd284b7cbe76f52022-12-22T03:11:43ZfasGolestan University of Medical Sciencesمجله دانشگاه علوم پزشکی گرگان1562-47652008-40802012-12-011447075Diagnostic value of high resolution computed tomographic scan in active pulmonary tuberculosisKhodabakhshi (MD)0Asali A (MD)1Behnampour N (MSc)2Abbasi A (MD)3Adel Barkhordar AR (MD)4Hashemi Frad A5 Associate Professor, Department of Infectious Diseases, Golestan University of Medical Sciences, Golestan Research Center of Gastroentrology and Hepatology, Gorgan, Iran Asisstant Professor, Radiologist, Department of Infectious Diseases, Golestan University of Medical Sciences, Gorgan, Iran Academic Insrtuctor, Department of Public Health, School of Health, Hematology and Oncology Research Center, Golestan University of Medical Sciences,Gorgan, Iran Associate Professor, Department of Infectious Diseases, Golestan University of Medical Sciences, Golestan Research Center of Infectious Diseases, Gorgan, Iran General Physician Student of Medicine, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran Background and Objective: Since accurate and quick clinical and paraclinical diagnostic methods are not available, in some cases diagnosis of active pulmonary tuberculosis occurs after considerable time from the onset of disease. This study was designed to determine the diagnostic value of High Resolution Computed Tomographic (HRCT) scan in active pulmonary tuberculosis, in Gorgan, Golestan province, North of Iran. Materials and Methods: This diagnostic screening study was carried out on 135 (79 male and 56 female) hospitalized patients suspected with active pulmonary tuberculosis, and HRCT was used in their course of treatment as recommendation of their clinician. The patients were chosen from 5th Azar hosptial during 2009-10. Also it should be mentioned that patients were selected on avaliabity bases, and they were examined by smear, and sputum culture. The patients with negative smear and culture were set up as true healthy group (64 subjects). The lung or small nuddles in HRCT was considered as proper position of lung involvument in active lung pulmonary. The HRCT findings between the case group (71 subjects) and healthy group were compared. According to HRCT findings, the sensitivity and specifity were determined for each patient. Data were analyzed using SPSS-16 and Chi-Square test. Results: In this study, sensitivity, specificity, positive predictive value and negative predictive value of HRCT in active pulmonary tuberculosis were equal to 97.2%, 71.9%, 79.3% and 95.8% respectively. Involvement of upper and middle lobe of the right lung and upper lobe of the left lung were significantly higher than the control group (P<0.05). Conclusion: This study showed that HRCT has high sensitivity and specificity in diagnosis of active pulmonary tuberculosis and can be used as a quick diagnostic way in active pulmonary tuberculosis, especially in patients with strong clinical suspicion and negative smear.http://goums.ac.ir/journal/browse.php?a_code=A-10-1-634&slc_lang=en&sid=1Active pulmonary tuberculosisHigh resolution computed tomographic scanSmears of sputumCulture of sputum |
| spellingShingle | Khodabakhshi (MD) Asali A (MD) Behnampour N (MSc) Abbasi A (MD) Adel Barkhordar AR (MD) Hashemi Frad A Diagnostic value of high resolution computed tomographic scan in active pulmonary tuberculosis مجله دانشگاه علوم پزشکی گرگان Active pulmonary tuberculosis High resolution computed tomographic scan Smears of sputum Culture of sputum |
| title | Diagnostic value of high resolution computed tomographic scan in active pulmonary tuberculosis |
| title_full | Diagnostic value of high resolution computed tomographic scan in active pulmonary tuberculosis |
| title_fullStr | Diagnostic value of high resolution computed tomographic scan in active pulmonary tuberculosis |
| title_full_unstemmed | Diagnostic value of high resolution computed tomographic scan in active pulmonary tuberculosis |
| title_short | Diagnostic value of high resolution computed tomographic scan in active pulmonary tuberculosis |
| title_sort | diagnostic value of high resolution computed tomographic scan in active pulmonary tuberculosis |
| topic | Active pulmonary tuberculosis High resolution computed tomographic scan Smears of sputum Culture of sputum |
| url | http://goums.ac.ir/journal/browse.php?a_code=A-10-1-634&slc_lang=en&sid=1 |
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