Successful endovascular treatment of abdominal aortic rupture secondary to bacillus Calmette-Guérin vaccine

Bacillus Calmette-Guérin (BCG) vaccine has been successfully used to treat bladder cancer. However, sporadic cases of mycotic arterial aneurysms have been reported. These patients typically develop a Mycobacterium bovis infection of an existing aneurysm or graft. In the present report, we have descr...

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Main Authors: Andrew E. Liechty, MD, Albert Pacifico, MD, Peter Brant-Zawadzki, MD
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Journal of Vascular Surgery Cases and Innovative Techniques
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S246842872100191X
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author Andrew E. Liechty, MD
Albert Pacifico, MD
Peter Brant-Zawadzki, MD
author_facet Andrew E. Liechty, MD
Albert Pacifico, MD
Peter Brant-Zawadzki, MD
author_sort Andrew E. Liechty, MD
collection DOAJ
description Bacillus Calmette-Guérin (BCG) vaccine has been successfully used to treat bladder cancer. However, sporadic cases of mycotic arterial aneurysms have been reported. These patients typically develop a Mycobacterium bovis infection of an existing aneurysm or graft. In the present report, we have described the case of a patient with a ruptured nonaneurysmal abdominal aorta years after intravesicular BCG therapy. Emergent aortic endograft repair was successful. After subsequent evaluation confirmed M. bovis infection, the patient was treated with a prolonged course of antimycobacterial therapy. Vascular surgeons should maintain suspicion for atypical aortic ruptures in patients with exposure to intravesicular BCG therapy.
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spelling doaj.art-d7b6f0e0f0f84296836bb4f7c6c491582022-12-22T01:00:37ZengElsevierJournal of Vascular Surgery Cases and Innovative Techniques2468-42872022-03-01811922Successful endovascular treatment of abdominal aortic rupture secondary to bacillus Calmette-Guérin vaccineAndrew E. Liechty, MD0Albert Pacifico, MD1Peter Brant-Zawadzki, MD2Elson S. Floyd College of Medicine, Spokane, Wash; Correspondence: Andrew E. Liechty, MD, Elson S. Floyd College of Medicine, Spokane, WashProvidence Medical Center, Everett, WashProvidence Medical Center, Everett, WashBacillus Calmette-Guérin (BCG) vaccine has been successfully used to treat bladder cancer. However, sporadic cases of mycotic arterial aneurysms have been reported. These patients typically develop a Mycobacterium bovis infection of an existing aneurysm or graft. In the present report, we have described the case of a patient with a ruptured nonaneurysmal abdominal aorta years after intravesicular BCG therapy. Emergent aortic endograft repair was successful. After subsequent evaluation confirmed M. bovis infection, the patient was treated with a prolonged course of antimycobacterial therapy. Vascular surgeons should maintain suspicion for atypical aortic ruptures in patients with exposure to intravesicular BCG therapy.http://www.sciencedirect.com/science/article/pii/S246842872100191XBCG vaccineEVAR treatmentInfected graftMycotic pseudoaneurysmProphylaxis
spellingShingle Andrew E. Liechty, MD
Albert Pacifico, MD
Peter Brant-Zawadzki, MD
Successful endovascular treatment of abdominal aortic rupture secondary to bacillus Calmette-Guérin vaccine
Journal of Vascular Surgery Cases and Innovative Techniques
BCG vaccine
EVAR treatment
Infected graft
Mycotic pseudoaneurysm
Prophylaxis
title Successful endovascular treatment of abdominal aortic rupture secondary to bacillus Calmette-Guérin vaccine
title_full Successful endovascular treatment of abdominal aortic rupture secondary to bacillus Calmette-Guérin vaccine
title_fullStr Successful endovascular treatment of abdominal aortic rupture secondary to bacillus Calmette-Guérin vaccine
title_full_unstemmed Successful endovascular treatment of abdominal aortic rupture secondary to bacillus Calmette-Guérin vaccine
title_short Successful endovascular treatment of abdominal aortic rupture secondary to bacillus Calmette-Guérin vaccine
title_sort successful endovascular treatment of abdominal aortic rupture secondary to bacillus calmette guerin vaccine
topic BCG vaccine
EVAR treatment
Infected graft
Mycotic pseudoaneurysm
Prophylaxis
url http://www.sciencedirect.com/science/article/pii/S246842872100191X
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