Resilience to anhedonia-passive coping induced by early life experience is linked to a long-lasting reduction of Ih current in VTA dopaminergic neurons

Resilience to anhedonia-passive coping induced by early life experience is linked to a long-lasting reduction of Ih current in VTA dopaminergic neurons

Exposure to aversive events during sensitive developmental periods can affect the preferential coping strategy adopted by individuals later in life, leading to either stress-related psychiatric disorders, including depression, or to well-adaptation to future adversity and sources of stress, a behavi...

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Bibliographic Details
Main Authors: Sebastian Luca D'Addario, Matteo Di Segni, Ada Ledonne, Rosamaria Piscitelli, Lucy Babicola, Alessandro Martini, Elena Spoleti, Camilla Mancini, Donald Ielpo, Francesca R. D'Amato, Diego Andolina, Davide Ragozzino, Nicola B. Mercuri, Carlo Cifani, Massimiliano Renzi, Ezia Guatteo, Rossella Ventura
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Neurobiology of Stress
Subjects:
Early stress
Ih current
VTA
Resilience
In vivo pharmacology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352289521000321

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